Actively Recruiting

Phase Not Applicable
All Genders
NCT07431125

Surgical-Clinical Correlation in Unilateral Conductive Hearing Loss With Intact Tympanic Membrane

Led by Al-Azhar University · Updated on 2026-02-24

20

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Unilateral conductive hearing loss (UCHL) in the presence of an intact tympanic membrane represents a diagnostic challenge in otologic practice. In the absence of middle ear effusion or tympanic membrane pathology, stapes fixation secondary to otosclerosis is often considered the most probable diagnosis. However, although otosclerosis is traditionally regarded as a bilateral disease, clinical presentation may be unilateral due to asymmetric disease progression or subclinical contralateral involvement. Other etiologies, including congenital ossicular anomalies, ossicular discontinuity, tympanosclerosis without tympanic membrane involvement, or oval window abnormalities, may mimic otosclerosis both clinically and audiologically. Consequently, exploratory tympanotomy remains the gold standard for definitive diagnosis, allowing direct assessment of ossicular chain mobility and confirmation of stapes fixation. Correlating preoperative clinical suspicion with intraoperative findings is therefore essential to better define the true causes of unilateral conductive hearing loss with an intact tympanic membrane.

CONDITIONS

Official Title

Surgical-Clinical Correlation in Unilateral Conductive Hearing Loss With Intact Tympanic Membrane

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Unilateral conductive hearing loss or mixed hearing loss with intact tympanic membrane
  • Average airborne gap above 20 decibels
Not Eligible

You will not qualify if you...

  • Sensorineural hearing loss
  • Chronic otitis media
  • Tympanic membrane perforation
  • Previous ear surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Alazhar university Hopital in Assiut

Asyut, Asyut Governorate, Egypt, 17511

Actively Recruiting

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Research Team

T

tarek Mansour, head of research committe

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Surgical-Clinical Correlation in Unilateral Conductive Hearing Loss With Intact Tympanic Membrane | DecenTrialz