Actively Recruiting
Surgical-imaging Research on Obesity (SIRO)
Led by The Affiliated Hospital of Xuzhou Medical University · Updated on 2024-03-15
200
Participants Needed
1
Research Sites
300 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The global obesity epidemic is well established, and is an important public health issue. The previous researches had applied the clues that obesity is a kind of systemic disease. The investigators hypothesized that a serious alteration of the body systems will occur after bariatric surgery, which may shed light on the mechanisms of obesity. Thus, the research aims to combine the imaging and surgery to investigate the alterations of the body that induced by obese and alterations after surgery.
CONDITIONS
Official Title
Surgical-imaging Research on Obesity (SIRO)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Meet obesity criteria with BMI greater than 28 and plan to undergo bariatric surgery for the first time
- Aged 18 to 65 years, any gender
- Right-handed and of Han ethnicity
- Willing and able to sign informed consent and cooperate with the research
- For control group: healthy volunteers with BMI between 18.5 and 23.9, aged 18 to 65 years, right-handed, of Han ethnicity, willing to cooperate and sign consent
You will not qualify if you...
- Secondary obesity caused by other diseases or medications such as hormone use
- Unable to undergo planned surgery
- Pregnant or breastfeeding
- Low cognitive ability or unable to cooperate with the study
- Eating disorders
- Alcohol or drug dependence
- Severe mental illnesses needing intervention, including schizophrenia and organic mental disorders
- Contraindications for MR scanning, including pacemakers, cochlear implants, metal in body, claustrophobia, or weight above machine limit
- History of neurological diseases such as brain tumors, epilepsy, stroke, or severe head trauma
- History of congenital heart diseases or serious heart conditions
- Severe dysfunction of liver, kidney, lung, digestive, endocrine, or blood systems
- Active infections in past two weeks such as fever or respiratory infections
- Use of nervous system affecting drugs or psychotropic drugs within last six months
- Control group excludes participants who meet exclusion criteria from points 3 to 13 above
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Affiliated Hospital of Xuzhou Medical University
Xuzhou, Jiangsu, China, 221000
Actively Recruiting
Research Team
K
Kai Liu, Prof.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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