Actively Recruiting
Surveillance MRI Registry for Patients Who Had Breast Cancer With Dense Breast Tissue
Led by M.D. Anderson Cancer Center · Updated on 2026-02-13
1000
Participants Needed
1
Research Sites
294 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To create a registry (database) of participants who come in for breast MRI scans. Researchers want to use this information to study if participants with dense breast tissue (tissue that is more difficult to see on mammogram).
CONDITIONS
Official Title
Surveillance MRI Registry for Patients Who Had Breast Cancer With Dense Breast Tissue
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants 50 years of age or younger with personal history of breast cancer and mammographically dense breasts (ACR Category C or D)
- Participants must be 18 years of age or older
- Participants scheduled for routine screening mammogram and/or digital breast tomosynthesis with negative or benign findings
- Participants must not be pregnant or breastfeeding; if of childbearing potential, pregnancy must be ruled out by blood or urine test within 2 weeks prior to enrollment
- Breast density must be known from prior mammogram or agreed to have mammogram/DBT before enrollment
- Participants must be asymptomatic for breast disease and undergoing routine screening
- No untreated breast cancer or current treatment or planned surgery for high-risk breast lesions at enrollment
- Participants on Tamoxifen may enroll
- BRCA mutation carriers, other genetic mutation carriers, and high-risk participants per ACS guidelines can participate
- Must be able to undergo breast MRI with contrast enhancement
- No history of untreatable claustrophobia
- No non-MRI compatible metallic objects or contraindications to MRI
- No history of sickle cell disease
- No contraindication to intravenous contrast
- No known allergy-like reaction to gadolinium or severe allergic reactions unless pre-treatment is possible
- No known or suspected renal impairment per local standards
- Weight must be within MRI table limits
- Ability to understand and sign informed consent
You will not qualify if you...
- Metastatic breast cancer
- Medically unstable condition
- Known contraindications to MRI
- Allergic reactions to paramagnetic contrast agents or severe allergic diathesis
- On renal dialysis or have renal dysfunction
- Received chemotherapy or hormonal therapy for cancer within previous 6 months
- Breast surgery or radiotherapy to the same breast within past 6 months
- History of serious breast trauma within past 3 months
- Pregnant or breastfeeding
- Disability preventing MRI in prone position
- Presence of some MR conditional implants such as neurostimulators or cardiac monitors per institutional policy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
MD Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
H
Huong Le-Petross, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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