Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT05894694

Survival Benefit of Compound Kushen Injection in the Treatment of Advanced Colorectal Cancer

Led by Guang'anmen Hospital of China Academy of Chinese Medical Sciences · Updated on 2024-12-27

320

Participants Needed

1

Research Sites

118 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To clarify the effectiveness and safety of compound kushen injection in the treatment of advanced colorectal cancer.

CONDITIONS

Official Title

Survival Benefit of Compound Kushen Injection in the Treatment of Advanced Colorectal Cancer

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with advanced colorectal cancer confirmed by pathology or cytology and receiving first-line therapy
  • Age 18 years or older, male or female
  • ECOG performance status score between 0 and 2
  • Expected survival of 3 months or more
  • At least one measurable lesion according to RECIST 1.1 criteria
  • Willing to participate voluntarily, sign informed consent, and comply with follow-up requirements
Not Eligible

You will not qualify if you...

  • Presence of other primary malignant tumors
  • Patients with MSI-H/dMMR status based on immunohistochemistry, PCR, or sequencing
  • Recurrence or metastasis within 6 months after radical tumor surgery
  • Previous or ongoing cancer immunotherapy
  • Patients currently receiving radiation therapy
  • Pregnant or breastfeeding women; women of childbearing age and their partners must use effective contraception during and for 6 months after the study
  • Psychiatric patients
  • Severe, uncontrolled organic diseases or infections such as decompensated heart, lung, or kidney failure that prevent chemotherapy
  • Participation in clinical trials of small molecule drugs within 28 days or large molecule drugs within 3 months
  • Known allergy or intolerance to study drugs

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Guang 'anmen Hospital, China Academy of Chinese Medical Sciences

Beijing, China

Actively Recruiting

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Research Team

J

jie Li

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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