Actively Recruiting

Phase 2
Age: 18Years - 80Years
All Genders
NCT06535893

Sustainable and Efficient Platform Trial of New Therapeutic Development for Early Breast Cancer

Led by Nagoya City University · Updated on 2025-11-20

100

Participants Needed

1

Research Sites

830 weeks

Total Duration

On this page

Sponsors

N

Nagoya City University

Lead Sponsor

J

Japan Clinical Oncology Group

Collaborating Sponsor

AI-Summary

What this Trial Is About

Randomized phase II trial targeting early-stage breast cancer (stage II-III) applicable to preoperative chemotherapy (NAC), comparing standard treatment with multiple experimental treatments.

CONDITIONS

Official Title

Sustainable and Efficient Platform Trial of New Therapeutic Development for Early Breast Cancer

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically or cytologically confirmed invasive breast carcinoma
  • Stage II or III breast cancer
  • ECOG performance status of 0 or 1
  • Age between 18 and 80 years
Not Eligible

You will not qualify if you...

  • Continuous use of steroid drugs or other immunosuppressants
  • History or presence of interstitial lung disease or pulmonary fibrosis
  • Infection requiring systemic treatment
  • Active second cancer, except for completely resected basal cell carcinoma, squamous cell carcinoma at clinical stage I, carcinoma in situ, mucosal carcinoma, superficial bladder carcinoma, gastrointestinal cancer curatively resected by ESD or EMR, or other cancers without recurrence for more than 5 years

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Nagoya City University

Nagoya, Aichi-ken, Japan, 467-8601

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Sustainable and Efficient Platform Trial of New Therapeutic Development for Early Breast Cancer | DecenTrialz