Actively Recruiting

Phase 1
Age: 35Years - 85Years
All Genders
Healthy Volunteers
NCT05254574

Sustained Acoustic Medicine for Osteoarthritis Pain

Led by ZetrOZ, Inc. · Updated on 2025-02-27

200

Participants Needed

1

Research Sites

223 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to compare Sustained Acoustic Medicine treatment to topical pain relief gel for the symptomatic management of osteoarthritis. The study will measure pain and function scores for patients undergoing treatment.

CONDITIONS

Official Title

Sustained Acoustic Medicine for Osteoarthritis Pain

Who Can Participate

Age: 35Years - 85Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Have physician-diagnosed mild to moderate knee, shoulder, elbow, ankle, hip, or spine osteoarthritis (OARSI atlas grades 1-2) or Degenerative Joint Disease
  • Fulfill the American College of Rheumatology clinical and radiological diagnostic criteria for knee osteoarthritis
  • Are between 35 and 85 years of age
  • Report a frequent pain score between 3 and 7 (on a 0-10 scale) during the week before enrollment
  • Report that knee, shoulder, elbow, ankle, hip, or spine pain negatively affects quality of life
  • Are willing not to use any cream, gel, or topical solution during treatment other than the approved study treatment
  • Are deemed appropriate by their physician or study site physician to participate
  • Are willing and able to self-administer treatment daily at home or during normal daily activity, excluding water activities that submerge the device
  • Do not use or start opioid or non-opioid analgesic medications
  • Are willing to stop any other interventional treatments on the affected area during the study (e.g., electrical nerve stimulation, muscle stimulation, traditional ultrasound)
Not Eligible

You will not qualify if you...

  • Cannot demonstrate the ability to put on and take off the study device
  • Have any condition that makes participation unacceptable, including inability to understand or follow instructions
  • Participated in a clinical trial for an investigational drug or agent within 30 days before screening
  • Are pregnant
  • Are a prisoner
  • Have a pacemaker
  • Have malignancy in the treatment area
  • Have an active infection, open sores, or wounds in the treatment area
  • Have impaired sensation in the treatment area (e.g., due to chemotherapy or anesthesia)
  • Have a known neuropathy affecting brain or spinal nerves
  • Have a hereditary tendency for excessive bleeding
  • Have had knee, shoulder, elbow, ankle, or hip replacement or other surgery in the affected area within the past 6 months
  • Require oxygen support
  • Have an allergy to aspirin or other NSAIDs
  • Have a secondary cause of arthritis such as metabolic or inflammatory arthritis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

James A Haley Veterans Hospital

Tampa, Florida, United States, 33511

Actively Recruiting

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Research Team

G

George K. Lewis, Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Sustained Acoustic Medicine for Osteoarthritis Pain | DecenTrialz