Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT05599750

Suture Repair vs Mesh Repair for Incisional Hernia

Led by Clayton Petro · Updated on 2026-01-07

154

Participants Needed

5

Research Sites

463 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this randomized controlled trial is to compare the difference in quality of life at one year postoperatively for patients undergoing incisional hernia repair with mesh versus suture repair using modern techniques. The main question it aims to answer are: • Determine if primary suture repair is non-inferior to mesh repair for incisional hernias 2-6cm with respect to quality of life using the HerQLes summary score at one year postoperatively.

CONDITIONS

Official Title

Suture Repair vs Mesh Repair for Incisional Hernia

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults >18 years old
  • Anticipated hernia defect 2-6cm in width
  • Non-emergent case
  • CDC class I
  • Patients who previously underwent primary ventral hernia repair without the use of mesh
  • Incisional hernia
Not Eligible

You will not qualify if you...

  • Emergent cases
  • Patients < 18 years old
  • Patients who are pregnant
  • Patients who previously underwent a prior ventral hernia repair with mesh at the site of the intended repair. Abdominal mesh in separate locations would be allowed.
  • Ventral hernia <2cm or > 6 cm in width
  • Primary hernia
  • CDC wound class II-IV

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

University of Florida

Gainesville, Florida, United States, 32611

Actively Recruiting

2

Northwestern

Chicago, Illinois, United States, 60611

Actively Recruiting

3

Cleveland Clinic Main Campus

Cleveland, Ohio, United States, 44195

Actively Recruiting

4

The Ohio State University Wexner Medical Center

Columbus, Ohio, United States, 43210

Not Yet Recruiting

5

Vanderbilt University

Nashville, Tennessee, United States, 37232

Actively Recruiting

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Research Team

C

Clayton Petro, MD

CONTACT

W

William Bennett, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Suture Repair vs Mesh Repair for Incisional Hernia | DecenTrialz