Actively Recruiting

Phase 1
Phase 2
Age: 50Years +
All Genders
Healthy Volunteers
NCT05465538

SV2A in Older Adults

Led by Yale University · Updated on 2026-02-27

24

Participants Needed

1

Research Sites

273 weeks

Total Duration

On this page

Sponsors

Y

Yale University

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The aim of the study is to examine the effect of cannabis use on brain synaptic density among older adults using \[11C\]UCB-J PET imaging.

CONDITIONS

Official Title

SV2A in Older Adults

Who Can Participate

Age: 50Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Able to provide informed consent
  • Male or female, aged 50 years or older
  • No history of significant medical or neurological disease
  • Body mass index (BMI) 50 or less
  • If woman of childbearing potential, agrees to use acceptable birth control during the study and up to one month after PET scans
Not Eligible

You will not qualify if you...

  • Women with a positive pregnancy test or who are lactating
  • Exposure to ionizing radiation exceeding recommended limits when combined with study tracer
  • History of bleeding disorder or current use of anticoagulants
  • Blood donation within 8 weeks prior to the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Conneticut Mental Health Center

New Haven, Connecticut, United States, 06519

Actively Recruiting

Loading map...

Research Team

A

Angerlyk Frytz, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here