Actively Recruiting
Sweden Cancerome Analysis Network - Breast Recurrence (SCAN-B-rec)
Led by Lund University Hospital · Updated on 2025-09-16
2000
Participants Needed
2
Research Sites
618 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Prospective multicenter observational study to assess molecular drivers of metastatic breast cancer and disease evolution upon therapeutic pressure. The main aim is to develop and validate prognostic, predictive and pathogenic markers in clinically well-characterized population-based material of breast cancer tumors and the corresponding normal tissue.These data will be used to characterize recurrent breast cancer on a molecular level, study tumor evolution, develop biomarkers of response/resistance to targeted therapy in the metastatic setting, enroll patients on targeted treatment clinical studies and to elucidate mechanisms of resistance to therapy.
CONDITIONS
Official Title
Sweden Cancerome Analysis Network - Breast Recurrence (SCAN-B-rec)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with pathologically confirmed advanced breast cancer (ABC), including locally advanced inoperable disease and stage IV disease.
- Age > 18 years.
- Performance status according to Eastern Cooperative Oncology Group (ECOG) 64 2.
- ABC must be radiologically or clinically assessable by clinical examination, CT scan, MRI, bone scintigraphy, or PET.
- Radiological evaluation done maximum 6 weeks prior to inclusion.
- Signed informed consent according to ICH/GCP and national/local regulations.
You will not qualify if you...
- Untreated psychiatric disorders that impair the patient's ability to comply with study treatment or protocol.
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Lund University Hospital
Lund, Sweden, 221 85
Actively Recruiting
2
Lund University Hospital
Lund, Sweden, 221 85
Actively Recruiting
Research Team
K
Karolina Holm, PhD
CONTACT
C
Christel Reutersward, MSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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