Actively Recruiting
The Swedish BioFINDER - Primary Care Study
Led by Skane University Hospital · Updated on 2026-04-06
1200
Participants Needed
1
Research Sites
469 weeks
Total Duration
On this page
Sponsors
S
Skane University Hospital
Lead Sponsor
L
Lund University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The overall aim of the study is to improve the diagnostic accuracy of AD and cognitive impairment in primary care settings to ensure better care and treatment as well as facilitate correct referrals to specialized memory clinics. The investigators will strive to recruit diverse and representative populations of patients with subjective cognitive decline (SCD), mild cognitive impairment (MCI) and mild dementia. The specific aims of the study are to: 1. Improve the detection of mild cognitive impairment (MCI) and dementia in primary care. 2. Develop and evaluate cognitive tests, blood-based biomarkers and brain imaging methods that are suitable for accurate and early diagnosis of Alzheimer's disease (AD) in primary care. 3. To prospectively validate plasma AD biomarkers for diagnosis of patients with cognitive symptoms who are evaluated in primary care. 4. Determine whether blood AD biomarkers improve patient management in primary care.
CONDITIONS
Official Title
The Swedish BioFINDER - Primary Care Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient seeks medical help due to cognitive symptoms or the doctor suspects a progressive neurodegenerative disorder
- Main symptoms include memory, executive, visuo-spatial, language, or attention complaints
- Age 40 years or older
- Has subjective cognitive decline, mild cognitive impairment, or mild dementia
You will not qualify if you...
- Already diagnosed with dementia
- Has a significant unstable systemic illness or organ failure that hinders participation
- Current significant alcohol or substance misuse
- Refuses evaluation at the Memory clinic
- Cognitive impairment caused by acute stroke
- Cognitive impairment clearly explained by another condition such as anemia, infection, severe sleep deprivation, psychotic disorder, moderate-severe depression, or alcohol abuse
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Primary care centers in Region Skåne
Malmö, Sweden
Actively Recruiting
Research Team
S
Sebastian Palmqvist, MD, PhD
CONTACT
E
Erik Stomrud, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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