Using Oral Sugar Water to Reduce Pain in Infants During Flexible Nasolaryngoscopy A Study at SickKids Pediatric Otolaryngology Clinic

What this Trial Is About

Researchers are studying whether oral sucrose sugar water containing 24% sucrose can reduce pain and distress in infants undergoing flexible nasolaryngoscopy, a procedure used to examine the nasal and throat areas. This study takes place in an outpatient setting at the SickKids Pediatric Otolaryngology Clinic and aims to understand how sucrose affects pain scores and other measures in babies during this procedure. Participants will be randomly assigned to receive either sterile water without sugar placebo or sugar water with 24% sucrose before the nasolaryngoscopy. The sucrose solution is not classified as a drug by Health Canada. The study uses a quadruple masking method, meaning that participants, caregivers, and researchers do not know which solution is given. This helps compare the effects of the sugar water to sterile water more accurately. During the study visit, researchers will measure pain scores, crying time, heart rate, time to baseline, skin conductance, visit duration, and caregiver impressions in infants up to 7 months old. Caregivers provide consent, and infants are monitored closely during and after the procedure to assess these outcomes. The total participation spans the scheduled clinic appointment when the flexible nasolaryngoscopy is performed.

Be Sweet to Babies During Nasolaryngoscopy