Actively Recruiting
The Sweet Kids Study (Stevia on Weight and Energy Effect Over Time)
Led by Arkansas Children's Hospital Research Institute · Updated on 2025-12-22
150
Participants Needed
2
Research Sites
166 weeks
Total Duration
On this page
Sponsors
A
Arkansas Children's Hospital Research Institute
Lead Sponsor
C
Cargill
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is an 8 to14-week three-arm randomized controlled in children 8 to 12 years old. The main purpose of the study is to evaluate if stevia has benefits for weight control and metabolic function relative to caloric sweeteners, and whether it provides benefits in this regard similar to water.
CONDITIONS
Official Title
The Sweet Kids Study (Stevia on Weight and Energy Effect Over Time)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 8-12 years
- Normal weight: BMI percentile 5th to less than 85th
- Excessive weight: BMI percentile 85th and less than 140% of the 95th percentile or BMI 35 to less than 40 kg/m2
- Current consumption of sugar sweetened beverages at least 2 times per week
- Low consumption of non-nutritive sweeteners 3 times per week or less
- Willingness to consume experimental products
You will not qualify if you...
- Children with class 3 obesity (BMI 140% or more of the 95th percentile or BMI 40.0 kg/m2 or higher)
- Dislike of experimental beverage taste
- Asthma requiring daily use of inhalers to control symptoms
- Asthma requiring rescue inhalers more than 2 days per week
- Exercise induced asthma
- Autism spectrum disorder (including Autistic disorder, Rett disorder, Asperger disorder, childhood disintegrative disorder, PDD-NOS)
- ADHD currently under medication
- Oppositional defiant disorder
- Epilepsy
- Cancer
- Chronic kidney disease
- Endocrine disorders (e.g., hypothyroidism, growth hormone deficiency)
- Autoimmune diseases (e.g., lupus, thyroiditis, juvenile idiopathic arthritis)
- Bleeding disorders (e.g., hemophilia)
- Chronic infections (e.g., HIV, hepatitis B, hepatitis C)
- Mental health disorders (e.g., depression, anxiety)
- Type 1 or type 2 diabetes mellitus
- Other medical conditions or medications affecting study outcomes as determined by investigators
- Refusal to have blood drawn during screening or consent
- Fasting glucose 126 mg/dl or higher at enrollment
- Fasting A1C 6.5% or higher at enrollment
- Completion of antibiotics less than 2 months prior
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Arkansas Children's Nutrition Center
Little Rock, Arkansas, United States, 72202
Actively Recruiting
2
Arkansas Children's Nutrition Center
Little Rock, Arkansas, United States, 72202
Actively Recruiting
Research Team
E
Eva C Diaz, M.D.
CONTACT
M
Mario Ferruzzi, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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