Actively Recruiting
Swiss Paediatric Airway Cohort for Children and Adolescents with Respiratory Symptoms in Switzerland
Led by University of Bern · Updated on 2026-04-21
6000
Participants Needed
12
Research Sites
195 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The Swiss Paediatric Airway Cohort (SPAC) is a national, ongoing study focused on children and adolescents in Switzerland who visit doctors for repeated wheezing, coughing, and breathing problems related to exercise or sleep. It aims to improve understanding of different clinical types, outcomes, diagnoses, and treatments for these respiratory issues. The study collects real-world data from routine care without performing tests solely for research purposes. Participants are children aged 0 to 16 years referred to paediatric pulmonary outpatient clinics across 10 Swiss hospitals and clinics. Families complete detailed questionnaires at the start, providing information on symptoms, medical history, treatments, and environmental factors. Lung function, allergy, blood, or other tests are done only if needed for clinical care. Follow-up includes monthly questionnaires for the first year and annual questionnaires thereafter to track symptoms and treatments over time. During the study, caregivers and patients 14 years or older provide information through online or postal questionnaires. Medical records from hospitals contribute data on clinical findings, diagnoses, and treatments. The study's main outcomes measured after one year include wheezing, coughing (excluding colds), exercise-induced breathing difficulty, and lung function changes. The study plans long-term follow-up with yearly assessments and continues until 2030, supporting research on healthcare and respiratory problems in children.
CONDITIONS
Brief Title
Swiss Paediatric Airway Cohort
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children and adolescents aged 0-16 years
- Resident in Switzerland
- Seen in a paediatric pulmonary outpatient clinic due to respiratory problems
- Parents and patients above age 14 must be able to sign an informed consent form
You will not qualify if you...
- Prior diagnosis of cystic fibrosis
- Prior diagnosis of primary ciliary dyskinesia
- Prior diagnosis of severe heart disease
- Prior diagnosis of oncological disease
- Prior diagnosis of neuromuscular disease
- Prior diagnosis of severe disability
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) at a paediatric pulmonary outpatient clinic
Duration - Up to 5 years from inclusion
Participants who undergo routine care for respiratory symptoms are observed through questionnaires and medical record reviews without additional tests specifically for the study.
Baseline questionnaire, monthly online questionnaires during the first year, and yearly postal follow-up questionnaires thereafter
Trial Site Locations
Total: 12 locations
1
Vienna Open Medical Institute
Vienna, Austria
Completed
2
Children's hospital Aarau
Aarau, Switzerland
Active, Not Recruiting
3
University Children's hospital Basel, UKBB
Basel, Switzerland
Actively Recruiting
4
Institute of Social and Preventive Medicine
Bern, Switzerland, 3012
Actively Recruiting
5
University Children's Hospital Bern, Inselspital
Bern, Switzerland
Actively Recruiting
6
Children's Hospital Chur
Chur, Switzerland
Actively Recruiting
7
Pulmonology clinic, Horgen
Horgen, Switzerland
Actively Recruiting
8
University Children's hospital Lausane, CHUV
Lausanne, Switzerland
Actively Recruiting
9
Children's hospital Lucerne
Lucerne, Switzerland
Actively Recruiting
10
Children's hospital St. Gallen
Sankt Gallen, Switzerland
Active, Not Recruiting
11
Pulmonology clinic, Worb
Worb, Switzerland
Actively Recruiting
12
University Children's Hospital Zurich
Zurich, Switzerland
Actively Recruiting
Research Team
C
Claudia E Kuehni, Prof.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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