Actively Recruiting
Swiss Paediatric Airway Cohort
Led by University of Bern · Updated on 2026-04-21
6000
Participants Needed
12
Research Sites
677 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The Swiss Paediatric Airway Cohort (SPAC) is a national, prospective clinical cohort of children and adolescents who visit physicians in Switzerland for recurrent wheeze, cough, and exercise- or sleep-related respiratory problems. SPAC aims to answer important questions on clinical phenotypes, prognosis, diagnosis and treatment. SPAC is part of routine care, and only clinically indicated investigations are done. The comprehensive baseline assessment includes a detailed questionnaire to families, plus test results, diagnoses and treatments from hospital records. Follow-up is via monthly questionnaires the first 12 months and thereafter annual questionnaires to families, and data from follow-up visits. Currently, 4344 patients from 10 clinics and hospitals in Switzerland (Aarau, Basel, Bern, Chur, Horgen, Lausanne, Luzern, St. Gallen, Worb, Zurich) have been enrolled. SPAC provides real-life data on children visiting the Swiss health care system for common respiratory problems. It will provide a research platform for health services research, and for nested clinical and transitional studies. Publications and plain language summaries are listed on the study website: https://www.spac-study.ch/publikationen/
CONDITIONS
Official Title
Swiss Paediatric Airway Cohort
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children and adolescents aged 0-16 years
- Resident in Switzerland
- Seen in a paediatric pulmonary outpatient clinic due to respiratory problems
- Parents and patients above age 14 must be able to sign an informed consent form
You will not qualify if you...
- Prior diagnosis of cystic fibrosis
- Prior diagnosis of primary ciliary dyskinesia
- Prior diagnosis of severe heart disease
- Prior diagnosis of oncological disease
- Prior diagnosis of neuromuscular disease
- Prior diagnosis of severe disability
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 12 locations
1
Vienna Open Medical Institute
Vienna, Austria
Completed
2
Children's hospital Aarau
Aarau, Switzerland
Active, Not Recruiting
3
University Children's hospital Basel, UKBB
Basel, Switzerland
Actively Recruiting
4
Institute of Social and Preventive Medicine
Bern, Switzerland, 3012
Actively Recruiting
5
University Children's Hospital Bern, Inselspital
Bern, Switzerland
Actively Recruiting
6
Children's Hospital Chur
Chur, Switzerland
Actively Recruiting
7
Pulmonology clinic, Horgen
Horgen, Switzerland
Actively Recruiting
8
University Children's hospital Lausane, CHUV
Lausanne, Switzerland
Actively Recruiting
9
Children's hospital Lucerne
Lucerne, Switzerland
Actively Recruiting
10
Children's hospital St. Gallen
Sankt Gallen, Switzerland
Active, Not Recruiting
11
Pulmonology clinic, Worb
Worb, Switzerland
Actively Recruiting
12
University Children's Hospital Zurich
Zurich, Switzerland
Actively Recruiting
Research Team
C
Claudia E Kuehni, Prof.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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