Actively Recruiting

Age: 0Years - 16Years
All Genders
ID03505216

Swiss Paediatric Airway Cohort for Children and Adolescents with Respiratory Symptoms in Switzerland

Led by University of Bern · Updated on 2026-04-21

6000

Participants Needed

12

Research Sites

195 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The Swiss Paediatric Airway Cohort (SPAC) is a national, ongoing study focused on children and adolescents in Switzerland who visit doctors for repeated wheezing, coughing, and breathing problems related to exercise or sleep. It aims to improve understanding of different clinical types, outcomes, diagnoses, and treatments for these respiratory issues. The study collects real-world data from routine care without performing tests solely for research purposes. Participants are children aged 0 to 16 years referred to paediatric pulmonary outpatient clinics across 10 Swiss hospitals and clinics. Families complete detailed questionnaires at the start, providing information on symptoms, medical history, treatments, and environmental factors. Lung function, allergy, blood, or other tests are done only if needed for clinical care. Follow-up includes monthly questionnaires for the first year and annual questionnaires thereafter to track symptoms and treatments over time. During the study, caregivers and patients 14 years or older provide information through online or postal questionnaires. Medical records from hospitals contribute data on clinical findings, diagnoses, and treatments. The study's main outcomes measured after one year include wheezing, coughing (excluding colds), exercise-induced breathing difficulty, and lung function changes. The study plans long-term follow-up with yearly assessments and continues until 2030, supporting research on healthcare and respiratory problems in children.

CONDITIONS

Brief Title

Swiss Paediatric Airway Cohort

Who Can Participate

Age: 0Years - 16Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children and adolescents aged 0-16 years
  • Resident in Switzerland
  • Seen in a paediatric pulmonary outpatient clinic due to respiratory problems
  • Parents and patients above age 14 must be able to sign an informed consent form
Not Eligible

You will not qualify if you...

  • Prior diagnosis of cystic fibrosis
  • Prior diagnosis of primary ciliary dyskinesia
  • Prior diagnosis of severe heart disease
  • Prior diagnosis of oncological disease
  • Prior diagnosis of neuromuscular disease
  • Prior diagnosis of severe disability

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person) at a paediatric pulmonary outpatient clinic

Surveillance

Duration - Up to 5 years from inclusion

Participants who undergo routine care for respiratory symptoms are observed through questionnaires and medical record reviews without additional tests specifically for the study.

Baseline questionnaire, monthly online questionnaires during the first year, and yearly postal follow-up questionnaires thereafter

Trial Site Locations

Total: 12 locations

1

Vienna Open Medical Institute

Vienna, Austria

Completed

2

Children's hospital Aarau

Aarau, Switzerland

Active, Not Recruiting

3

University Children's hospital Basel, UKBB

Basel, Switzerland

Actively Recruiting

4

Institute of Social and Preventive Medicine

Bern, Switzerland, 3012

Actively Recruiting

5

University Children's Hospital Bern, Inselspital

Bern, Switzerland

Actively Recruiting

6

Children's Hospital Chur

Chur, Switzerland

Actively Recruiting

7

Pulmonology clinic, Horgen

Horgen, Switzerland

Actively Recruiting

8

University Children's hospital Lausane, CHUV

Lausanne, Switzerland

Actively Recruiting

9

Children's hospital Lucerne

Lucerne, Switzerland

Actively Recruiting

10

Children's hospital St. Gallen

Sankt Gallen, Switzerland

Active, Not Recruiting

11

Pulmonology clinic, Worb

Worb, Switzerland

Actively Recruiting

12

University Children's Hospital Zurich

Zurich, Switzerland

Actively Recruiting

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Research Team

C

Claudia E Kuehni, Prof.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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