Actively Recruiting

Age: 0 - 36Years
All Genders
NCT05017142

Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)

Led by University of Bern · Updated on 2024-12-16

500

Participants Needed

13

Research Sites

2646 weeks

Total Duration

On this page

Sponsors

U

University of Bern

Lead Sponsor

S

Schweizerische Multiple Sklerose Gesellschaft

Collaborating Sponsor

AI-Summary

What this Trial Is About

The Swiss-Ped-IBrainD is a national patient registry that collects information on diagnosis, symptoms, treatment, and follow-up of pediatric patients with an inflammatory brain disease in Switzerland. It was first implemented in 2020 in the pediatric clinic of the university hospital in Bern. Further centers all over Switzerland opened for recruitment after that: Aarau, Basel, Bellinzona, Chur, Geneva, Lausanne, Lucerne, St. Gallen, Winterthur and Zurich. The center in Fribourg is expected open for recruitment in 2025. The registry provides data for national and international monitoring and research. It supports research on inflammatory brain diseases in Switzerland and the exchange of knowledge between clinicians, researchers, and therapists. The registry aims to improve the treatment of children with inflammatory brain diseases and optimizing their health care and quality of life.

CONDITIONS

Official Title

Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)

Who Can Participate

Age: 0 - 36Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients living and/or treated in Switzerland diagnosed with an inflammatory brain disease from 2005 onward
  • Disease onset before the age of 18
  • Written informed consent by patients and/or legal representatives
  • Diagnosed with one of the following: optic neuritis, transverse myelitis, acute disseminated encephalomyelitis, multiple sclerosis, neuromyelitis optica spectrum disorders, myelin oligodendrocyte glycoprotein antibody-associated disease, anti-NMDA-R encephalitis, anti-GAD65 associated autoimmune encephalitis, anti-AMPAR-1/2 associated autoimmune encephalitis, anti-Lgi-1 associated autoimmune encephalitis, anti-CASPR-2 associated autoimmune encephalitis, anti-GABAR-1/2 associated autoimmune encephalitis, onconeuronal antibody associated autoimmune encephalitis, Hashimoto encephalopathy, CNS vasculitis, CNS sarcoidosis, CNS lupus, Rasmussen encephalitis
Not Eligible

You will not qualify if you...

  • Neurological symptoms caused by infectious diseases of the central nervous system
  • Genetic or metabolic causes of central demyelinating diseases
  • Neurological symptoms caused by Guillain-Barré syndrome

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 13 locations

1

Kantonsspital Aarau

Aarau, Canton of Aargau, Switzerland, 5001

Actively Recruiting

2

Children's Hospital of Eastern Switzerland

Sankt Gallen, Canton of St. Gallen, Switzerland, 9000

Actively Recruiting

3

University Children's Hospital Lausanne (CHUV)

Lausanne, Canton of Vaud, Switzerland, 1011

Actively Recruiting

4

Kantonsspital Winterthur

Winterthur, Canton of Zurich, Switzerland, 8400

Actively Recruiting

5

Pediatric Institute of Southern Switzerland, Ospedale San Giovanni

Bellinzona, Canton Ticino, Switzerland, 6500

Actively Recruiting

6

Kantonsspital Graubünden

Chur, Kanton Graubünden, Switzerland, 7000

Actively Recruiting

7

University Children's Hospital Basel, UKBB

Basel, Switzerland, 4031

Actively Recruiting

8

University Children's Hospital, Inselspital Bern

Bern, Switzerland, 3010

Actively Recruiting

9

Institute of Social and Preventive Medicine, University of Bern

Bern, Switzerland, 3012

Actively Recruiting

10

Hôpital Fribourgeois - Freiburger Spital

Fribourg, Switzerland, 1752

Not Yet Recruiting

11

University Hospitals of Geneva (HUG)

Geneva, Switzerland, 1211

Actively Recruiting

12

Kinderspital Zentralschweiz

Lucerne, Switzerland, 6000

Actively Recruiting

13

University Children's Hospital Zurich

Zurich, Switzerland, 8032

Actively Recruiting

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Research Team

L

Lorena F Hulliger, MSc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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