Actively Recruiting
Swiss ProspectivE Cohort of TRAnsgender and Gender Diverse Individuals - The SPECTRA Study
Led by University Hospital, Basel, Switzerland · Updated on 2026-05-05
600
Participants Needed
2
Research Sites
1028 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Basel, Switzerland
Lead Sponsor
U
University of Luzern
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this observational study is to understand the factors influencing the well-being and health of transgender and gender-diverse (TGD) individuals undergoing gender-affirming therapies in Switzerland. The study population includes TGD individuals aged 16 and older, at various stages of their medical transition, including those who have discontinued or detransitioned. The main question is: What are the key factors influencing the well-being and health outcomes of transgender and gender-diverse individuals undergoing gender-affirming therapies? Researchers will compare health outcomes across different subgroups, such as those at different stages of transition or detransition, to examine the effects of gender-affirming therapies. Participants will: Complete electronic questionnaires assessing gender congruence, quality of life, mental health, and other outcomes. Provide biological samples (e.g., blood, urine, stool, and skin swabs) for laboratory analysis. Undergo clinical evaluations related to endocrinology, fertility, dermatology, and urology as part of their routine follow-up.
CONDITIONS
Official Title
Swiss ProspectivE Cohort of TRAnsgender and Gender Diverse Individuals - The SPECTRA Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 16 years and above
- Established diagnosis of gender incongruence
- Indication for gender-affirming therapy or currently ongoing or discontinued gender-affirming therapy
You will not qualify if you...
- Unable to give informed consent
- Missing commitment or ability to follow study protocol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
University Hospital of Basel
Basel, Switzerland, 4031
Actively Recruiting
2
Cantonal Hospital of Lucerne
Lucerne, Switzerland, 6000
Not Yet Recruiting
Research Team
B
Bettina Winzeler, PD Dr.
CONTACT
H
Hüseyin Cihan, Dr.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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