Actively Recruiting
Switch or Quit R01
Led by Medical University of South Carolina · Updated on 2025-07-25
225
Participants Needed
1
Research Sites
146 weeks
Total Duration
On this page
Sponsors
M
Medical University of South Carolina
Lead Sponsor
N
National Institute on Drug Abuse (NIDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study evaluates whether non-cigarette tobacco products (e-cigarettes) can help smokers quit smoking as compared to traditional quit methods (nicotine replacement therapy or varenicline/Chantix). Participants in this study will be randomly assigned to one of two groups, then will have a choice between the offered products of that group. Participants in the e-cigarette group will have a choice of e-cigarette brand and flavor. Participants in the medication group will have choice between nicotine replacement therapy (patches and lozenges) or varenicline, also known as Chantix. Participation will last 6 months and will include weekly phone calls for the initial 7-weeks plus a 11-week phone call and a 6-month follow-up visit. Participants will also complete electronic daily diaries during the first 7-weeks.
CONDITIONS
Official Title
Switch or Quit R01
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 21 or older who have previously attempted to quit smoking using FDA-approved medications
- Interest in reducing harm from tobacco use or quitting smoking
You will not qualify if you...
- Pregnant, breastfeeding, or trying to become pregnant
- Living with someone currently enrolled in the study
- Planning to move away from the area within the next 7 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Medical Univeristy of South Carolina
Charleston, South Carolina, United States, 29425
Actively Recruiting
Research Team
T
Tracy Smith, PhD
CONTACT
M
Merritt McDonald
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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