Actively Recruiting
Symplicity China Study
Led by Medtronic Vascular · Updated on 2025-11-17
500
Participants Needed
1
Research Sites
320 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The Symplicity China study will evaluate the real-world long-term safety, efficacy, and durability of the Symplicity Spyral system in a population of approximately 500 renal denervation treated subjects with up to 36 months of follow up.
CONDITIONS
Official Title
Symplicity China Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 years or older.
- Diagnosed with resistant hypertension or antihypertensive drug intolerance and treated with Symplicity Spyral Renal Denervation System. Resistant hypertension is defined as having an office systolic blood pressure of 140 mmHg or higher despite appropriate lifestyle measures and treatment with three or more antihypertensive medications including a diuretic for more than 3 months; drug intolerance means the patient cannot tolerate medication due to contraindications or side effects.
- Voluntarily undergoes renal denervation and provides written informed consent after being informed about the study's observational nature.
You will not qualify if you...
- At least one main renal artery has a diameter less than 3 mm or greater than 8 mm.
- Presence of fibromuscular dysplasia.
- Renal artery stent placement within 3 months prior to the procedure.
- Presence of renal artery aneurysms.
- More than 50% stenosis in any treatable vessel.
- Pregnant.
- Presence of renal or adrenal tumors.
- Iliac or femoral artery stenosis preventing catheter insertion.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Zhongshan Hospital Fudan University
Shanghai, Shanghai Municipality, China, 210000
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here