Actively Recruiting

Phase Not Applicable
Age: 18Years - 64Years
All Genders
NCT06855186

Symptom-Targeted Approach to Rehabilitation for Concussion (STAR-C)

Led by Henry M. Jackson Foundation for the Advancement of Military Medicine · Updated on 2026-01-08

222

Participants Needed

2

Research Sites

154 weeks

Total Duration

On this page

Sponsors

H

Henry M. Jackson Foundation for the Advancement of Military Medicine

Lead Sponsor

B

Brooke Army Medical Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

Purpose: Investigators propose a three-arm RCT across two military treatment facilities:1) in-person STAR-C, 2) telehealth STAR-C, and 3) no treatment control. Outcomes will be assessed immediately and at one- and three-months post treatment. Hypothesis/Objectives: STAR-C, delivered in-person and via telehealth, will be effective in decreasing everyday cognitive complaints among patients with a history of mTBI. Effectiveness will be moderated by patient characteristics. Stakeholder feedback will yield a process map for broad implementation of STAR-C in varied clinical environments.

CONDITIONS

Official Title

Symptom-Targeted Approach to Rehabilitation for Concussion (STAR-C)

Who Can Participate

Age: 18Years - 64Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • History of mild traumatic brain injury (mTBI) sustained more than 3 months ago, defined by VA/DoD guidelines
  • Score of 2, 3, or 4 on any of the four Cognitive items on the Neurobehavioral Symptom Inventory (NSI)
  • Reading ability at a sixth-grade level or higher on the Word Reading Subtest of the Wide Range Achievement Test
Not Eligible

You will not qualify if you...

  • History of moderate, severe, or penetrating traumatic brain injury
  • Lifetime diagnosis of schizophrenia or other psychotic/thought disorder
  • Currently receiving intensive behavioral health treatment (3 or more appointments per week) for psychiatric or substance use disorders
  • Participation in cognitive-targeting treatments within the last two weeks exceeding 4 hours per week
  • History of neurological diseases affecting cognition, such as multiple sclerosis, stroke, brain tumor, or Parkinson Disease
  • Active suicidal or homicidal thoughts
  • Daily use of narcotic pain medications
  • Lack of access to technology or internet/cell phone service supporting telemedicine
  • Current participation in other cognitive-targeting therapy (excluding Cognitive Behavioral Therapy)

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Desmond T. Doss Health Clinic

Wahiawa, Hawaii, United States, 96786

Actively Recruiting

2

Brooke Army Medical Center

San Antonio, Texas, United States, 78234

Actively Recruiting

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Research Team

M

Marc Blaylock

CONTACT

K

Kalawena N Kalehuawehe

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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