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ID07510984

Observational Study on Swallowing and Digestive Symptoms in Adults Undergoing Gastroscopy to Detect Heterotopic Gastric Mucosa

Led by Knappschaft Kliniken GmbH · Updated on 2026-04-14

721

Participants Needed

1

Research Sites

14 weeks

Total Duration

AI-Summary

What this Trial Is About

Researchers are studying whether heterotopic gastric mucosa HGM, which are islands of stomach-like tissue in the upper esophagus, is linked to swallowing difficulties dysphagia in adults undergoing medically needed gastroscopy. The study also looks at connections between HGM and indigestion symptoms dyspepsia and their impact on quality of life. Participants with and without HGM will be compared to see if symptoms and quality-of-life measures differ between these groups. This is a prospective, observational study involving adults aged 18 and older who are scheduled for gastroscopy for any medical reason. Before the procedure, participants fill out questionnaires about dysphagia, dyspepsia, and quality of life. During the planned gastroscopy, doctors check for HGM without influencing the procedure. No extra procedures are required beyond the routine gastroscopy and any clinical tissue sampling. Participants complete detailed symptom and quality-of-life questionnaires before gastroscopy. The study collects data on swallowing difficulties, indigestion symptoms, and health-related quality of life using validated tools. The presence of HGM is recorded during routine endoscopy without revealing questionnaire answers to the doctor. Data will be analyzed to understand the relationship between HGM and symptoms. Total participation involves a single assessment before gastroscopy, with no additional follow-up required.

CONDITIONS

Brief Title

Symptoms and Quality of Life in Patients With Heterotopic Gastric Mucosa (HGM)

Research Team

F

Felix Horstmann, MD

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