Actively Recruiting
Synapse 3D With Intravascular Indocyanine Green
Led by St. Joseph's Healthcare Hamilton · Updated on 2026-02-02
32
Participants Needed
1
Research Sites
213 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
With the advent of CT screening for lung cancer, an increasing number of NSCLCs are being detected at very early stages, and the demand for pulmonary segmentectomy is rising rapidly. As such, there is a need to develop new surgical techniques to facilitate minimally invasive pulmonary segmentectomy, as segmentectomy may provide a number of significant advantages over lobectomy for patients presenting with early-stage lung cancer, or for patients unable to undergo a full lobectomy due to existing comorbidities. This study will provide the first case series using preoperative 3D anatomical planning (Synapse 3D) added to ICG and NIF-guided robotic segmentectomy to date and will be the first reported use of Synapse 3D-guided targeted pulmonary segmental resection in Canada. As lung cancer is the most frequently fatal cancer in North America, many thousands of patients will be able to benefit from this operation every year.
CONDITIONS
Official Title
Synapse 3D With Intravascular Indocyanine Green
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Tumor size less than 3 cm
- Clinical Stage 1 Non-Small Cell Lung Cancer (NSCLC)
- CT imaging confirms tumor is confined to one broncho-pulmonary segment, making segmental resection possible
You will not qualify if you...
- Allergy or hypersensitivity to ICG, sodium iodide, or iodine
- Women who are pregnant, breastfeeding, or of childbearing potential without adequate birth control
- Evidence of N1 or N2 disease on preoperative imaging
- Pulmonary function tests showing FEV1 or DLCO less than or equal to 30% of predicted
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
St. Josephs Healthcare Hamilton
Hamilton, Ontario, Canada, L8N 4A6
Actively Recruiting
Research Team
P
Peter R. A. Malik, BHSc (Honours)
CONTACT
Y
Yogita S Patel, BSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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