Actively Recruiting

Age: 1Year - 35Years
All Genders
NCT07473804

Syndromes With Neonatal Salt Loss: Not Only Congenital Adrenal Hyperplasia Due to 21-hydroxylase Deficiency (21OH-ISC)

Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2026-03-16

25

Participants Needed

1

Research Sites

89 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Neonatal salt loss can be caused not only by infections but also by rare endocrine disorders that resemble 21-hydroxylase deficiency but are not detected by neonatal screening. This study examines how often these conditions occur and describes their main clinical, genetic, and treatment features.

CONDITIONS

Official Title

Syndromes With Neonatal Salt Loss: Not Only Congenital Adrenal Hyperplasia Due to 21-hydroxylase Deficiency (21OH-ISC)

Who Can Participate

Age: 1Year - 35Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of endocrine-related salt loss with hyponatremia (serum sodium <130 mEq/L)
  • Salt loss onset between 0 and 60 days of life
  • Born between January 1, 1989 and December 31, 2023
  • Managed at the Experimental Center
  • Informed consent obtained
Not Eligible

You will not qualify if you...

  • Diagnosis of 21-hydroxylase deficiency (21OH ISC)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, Italy, 40138

Actively Recruiting

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Research Team

F

Federico Baronio

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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