Actively Recruiting

Phase 2
Age: 18Years +
All Genders
Healthy Volunteers
NCT07334977

Synergistic Effect of Non-invasive Brain and Spinal Cord Stimulation

Led by Centre National de la Recherche Scientifique, France · Updated on 2026-01-12

45

Participants Needed

2

Research Sites

155 weeks

Total Duration

On this page

Sponsors

C

Centre National de la Recherche Scientifique, France

Lead Sponsor

U

University Hospital, Bordeaux

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical study is to investigate the potential synergy between non-invasive brain and spinal cord stimulation administered during a cognitive-motor task, in terms of their immediate effects on sensorimotor and cognitive functions after neurological injuries affecting the upper limb (cervical spinal cord injury and stroke). Secondary objectives are to evaluate the relevance of anatomical MRI, functional MRI, and neurophysiological measurements for optimizing and predicting the effects of these different interventions.

CONDITIONS

Official Title

Synergistic Effect of Non-invasive Brain and Spinal Cord Stimulation

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Be over 18 years old
  • Have signed an informed consent form
  • Be affiliated with and covered by the social security system
  • For post-stroke participants: sustained a stroke more than 3 weeks ago and be medically stable
  • For spinal cord injury participants: have a complete or incomplete cervical spinal cord injury causing quadriplegia and be medically stable
Not Eligible

You will not qualify if you...

  • Have a chronic condition
  • Have skin problems or open wounds
  • Have a history of epilepsy or seizures
  • Have contraindications to magnetic or electrical stimulation or MRI, such as cardiac pacemaker, implanted hearing aid, intraocular foreign body, shrapnel, metal work exposure, neurostimulator, or claustrophobia
  • Have implanted medical devices not classified as MRI Conditional (e.g., cardiac valve, surgical clips, stents, hardware)
  • Be legally incompetent or under judicial protection, guardianship, or trusteeship
  • Be pregnant or breastfeeding
  • Refuse to be informed of any abnormalities detected by MRI

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Service de Médecine Physique & Réadaptation - CHU Bordeaux

Bordeaux, France, 33000

Actively Recruiting

2

Centre de la Tour de Gassies

Bruges, France, 33520

Actively Recruiting

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Research Team

N

Nabila Brihmat, PhD

CONTACT

F

Fabien Wagner, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

4

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Synergistic Effect of Non-invasive Brain and Spinal Cord Stimulation | DecenTrialz