Actively Recruiting

Age: 18Years +
FEMALE
NCT07284082

The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in Women

Led by University of California, San Francisco · Updated on 2026-04-22

90

Participants Needed

1

Research Sites

202 weeks

Total Duration

On this page

Sponsors

U

University of California, San Francisco

Lead Sponsor

N

National Heart, Lung, and Blood Institute (NHLBI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Menopause is associated with the acceleration of many comorbidities, including cardiovascular disease. Whether HIV and menopause together increase cardiovascular disease risk is a key knowledge gap. The goal of this observational study is to address this knowledge gap by looking at the role of menopause on cardiovascular disease risk factors such as insulin resistance, hypertension, hyperlipidemia, and carotid atherosclerosis using previously collected data. The investigators will look at underlying causes for cardiovascular diseases worsening in menopausal women with HIV by looking at the role of increased inflammation in the body and whether this is altered by weight. The investigators achieve this by enrolling participants who are willing to undergo a whole body MRI.

CONDITIONS

Official Title

The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in Women

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Non-pregnant women with HIV
  • Approximately 90 participants from the San Francisco MWCCS site
  • Includes about 30 women in each menopausal phase
Not Eligible

You will not qualify if you...

  • Women not virally suppressed (HIV RNA >200 copies/mL)
  • Women not on antiretroviral therapy
  • Women with a history of hysterectomy or oophorectomy
  • Women receiving treatment for active cancer or tuberculosis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of California, San Francisco

San Francisco, California, United States, 94110

Actively Recruiting

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Research Team

R

Rebecca A Abelman, MD

CONTACT

S

Stacy Polos

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in Women | DecenTrialz