Actively Recruiting

Phase Not Applicable
Age: 18Years - 55Years
All Genders
NCT07058389

Synergy Between Physical Activity and Outdoor Green Environments to Reduce the Intensity of Negative Symptoms in Schizophrenia.

Led by Centre Hospitalier Universitaire de Saint Etienne · Updated on 2025-11-25

45

Participants Needed

1

Research Sites

112 weeks

Total Duration

On this page

Sponsors

C

Centre Hospitalier Universitaire de Saint Etienne

Lead Sponsor

J

Jean Monnet University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Physical activity appears to be a novel and original adjunctive therapeutic approach in the management of patients with schizophrenia. It may help reduce schizophrenic symptoms, act as a pro-cognitive therapy, improve quality of life, and reduce cardiovascular comorbidities. Moreover, some evidence suggests that physical activity practiced in a natural environment has even more positive effects on mental health compared to physical activity carried out indoors or in urban settings. Indeed, greater exposure to greenery is associated with a better perception of general health and with reduced levels of cortisol, anxiety, and depression. No study has yet attempted to examine the impact of physical activity in green (outdoor) spaces compared to indoor physical activity on the negative symptoms of patients suffering from schizophrenia. The aim of this study is therefore to test this hypothesis.

CONDITIONS

Official Title

Synergy Between Physical Activity and Outdoor Green Environments to Reduce the Intensity of Negative Symptoms in Schizophrenia.

Who Can Participate

Age: 18Years - 55Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with schizophrenia, aged 18 to 55 years
  • Having persistent negative symptoms (SNS), negative symptoms self-assessment scale > 7
  • Regularly monitored in the psychiatry department
  • Have no medical contraindications to physical activity
  • Subject affiliated with or entitled to a social security system
  • Subject having received informed information about the study and having co-signed, with the investigator, consent to participate in the study
  • Male or female
Not Eligible

You will not qualify if you...

  • Patient unsuitable for study in the opinion of the investigator
  • Any subject with chronic joint pathologies (example: repeated sprains, patellar or ligament problems) or cardiac pathologies
  • Any subject presenting chronic or central neurological pathologies
  • Any subject deprived of liberty or subject to legal protection
  • Excessive consumption of alcohol (> 14 glasses per week) or caffeinated drinks (> 400 mg of coffee per day)
  • Pregnant women
  • Subject unable to understand the purpose and conditions of the study, unable to give consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHU de Saint-Etienne

Saint-Etienne, France, France, 42055

Actively Recruiting

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Research Team

M

Medhi HOUSNI, Md

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

3

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