Actively Recruiting

Age: 18Years +
All Genders
NCT07035938

T-cell Developmental Status in Patients With Malignant Hematological Tumors

Led by The First Affiliated Hospital of Xiamen University · Updated on 2025-07-23

75

Participants Needed

1

Research Sites

157 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To evaluate the immune status and prognosis of patients with malignant hematological tumors, thereby guiding clinical therapeutic strategies.

CONDITIONS

Official Title

T-cell Developmental Status in Patients With Malignant Hematological Tumors

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older; both genders included; expected survival more than 3 months
  • Patients with newly diagnosed or relapsed B-cell lymphoma confirmed by histopathology, bone marrow pathology, flow cytometry, morphology, and genetic testing
  • Patients with newly diagnosed or relapsed multiple myeloma confirmed by histopathology, bone marrow pathology, flow cytometry, morphology, and genetic testing
  • Healthy volunteers
  • Able to understand and voluntarily sign the informed consent form
Not Eligible

You will not qualify if you...

  • Chronic obstructive pulmonary disease (COPD) with forced expiratory volume in 1 second (FEV1) less than 50% of predicted normal value
  • Moderate or severe persistent asthma within the past 2 years, or currently uncontrolled asthma of any severity
  • Symptomatic congestive heart failure (NYHA Class II-IV), symptomatic or uncontrolled arrhythmias, congenital long QT syndrome, or corrected QT interval (QTc) greater than 500 ms at screening
  • History of pulmonary fibrosis, interstitial pneumonia, pneumoconiosis, drug-related pneumonitis, or severely impaired lung function
  • HIV infection (positive HIV-1/2 antibodies) or known syphilis infection
  • Unhealed wounds, fractures, gastroduodenal ulcers, persistent fecal occult blood positivity, ulcerative colitis, or other conditions at risk of gastrointestinal bleeding or perforation
  • Severe neurological or psychiatric disorders, immunodeficiency, hepatitis or cirrhosis, or other conditions deemed unsuitable for study participation by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Zhijuan Lin

Xiamen, Fujian, China, 361000

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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