Actively Recruiting
Tailored Anti-Inflammatory (A-I) Diet for Americans With Ulcerative Colitis (UC)
Led by University of Miami · Updated on 2026-03-30
122
Participants Needed
1
Research Sites
286 weeks
Total Duration
On this page
Sponsors
U
University of Miami
Lead Sponsor
N
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to test the effect of an anti-inflammatory diet that incorporates native foods of the American diet on disease remission in American patients with Ulcerative Colitis (UC) and to identify biomarkers of response to dietary therapy.
CONDITIONS
Official Title
Tailored Anti-Inflammatory (A-I) Diet for Americans With Ulcerative Colitis (UC)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Documented diagnosis of ulcerative colitis from medical records
- Self-identify as American
- Aged between 16 and 75 years
- Simple Clinical Colitis Activity Index (SCCAI) score between 3 and 9
- Fecal calprotectin greater than 150 mg/dl
- Stable medications for ulcerative colitis for at least 3 months
- Likeability of American foods such as sandwiches, BBQ or grilled meats and vegetables, baked potatoes, smoothies, salmon, oatmeal, avocado, and soups
- No inflammatory bowel disease related hospitalization in the last month
You will not qualify if you...
- Diagnosis of Crohn's Disease
- Prior ileoanal anastomosis (J-pouch) or diversion surgery
- Hospitalizations in the last 4 weeks
- Clostridium difficile or other enteric infections in the last 4 weeks
- Use of probiotics in the last 4 weeks
- Following specific carbohydrate, Mediterranean, or anti-inflammatory diets
- Active cancer or medical conditions limiting diet adherence such as heart failure or end-stage renal disease
- Pregnancy, breastfeeding, or planning pregnancy during the study
- Use of Total Parenteral Nutrition at screening or during study
- Significant or life-threatening co-morbidities
- Need for antibiotic use during the study
- Adults unable to provide consent
- Age less than 16 or greater than 75 years
- Prisoners
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Miami Health System
Miami, Florida, United States, 33136
Actively Recruiting
Research Team
O
Oriana Damas, MD, MSCTI
CONTACT
E
Eytan I Stern, MS, RD, LD/N, CNSC
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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