Actively Recruiting
Tailored Electronic Intervention to Improve Therapy in a Diverse Cohort of Patients With Heart Failure
Led by Emory University · Updated on 2026-04-14
4000
Participants Needed
4
Research Sites
62 weeks
Total Duration
On this page
Sponsors
E
Emory University
Lead Sponsor
M
Merck Sharp & Dohme LLC
Collaborating Sponsor
AI-Summary
What this Trial Is About
Recent medical guidelines for the management of heart failure (HF) have established a combination of specific classes of medications as the best treatment for patients with heart failure with reduced ejection fraction (HFrEF). However, studies have shown that these medications, known together as guideline-directed medical therapy (GDMT), are not being used in clinical practice less often than they could be. Several tools to promote broader use of these treatments (including patient checklists) have shown promise for increasing use of GDMT. However, these tools have not been broadly implemented within large health systems. The goal of this study is to see if using these tools broadly within cardiology clinics will increase the use of GDMT. This study is important because it could help improve the use of GDMT, which may lead to improved patient care and outcomes.
CONDITIONS
Official Title
Tailored Electronic Intervention to Improve Therapy in a Diverse Cohort of Patients With Heart Failure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ejection fraction (EF) less than or equal to 40% by echocardiogram performed in the prior 18 months
- Diagnosis of heart failure
You will not qualify if you...
- Heart failure etiology for which GDMT is not indicated, including hypertrophic or restrictive cardiomyopathy, constrictive pericarditis, or complex congenital heart disease
- End-stage heart failure requiring continuous inotrope infusion, heart transplant, or left ventricular assist device
- Estimated glomerular filtration rate (eGFR) less than 15 mL/min/1.73m2
- Any other conditions likely to alter patient's status over 6 months, indicated by active hospice status
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Emory Saint Joseph's Hospital
Atlanta, Georgia, United States, 30308
Actively Recruiting
2
Emory University Hospital Midtown
Atlanta, Georgia, United States, 30308
Actively Recruiting
3
Emory University Hospital
Atlanta, Georgia, United States, 30322
Actively Recruiting
4
Emory Johns Creek Hospital
Johns Creek, Georgia, United States, 30097
Actively Recruiting
Research Team
N
Neal W Dickert, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
3
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