Actively Recruiting

Phase Not Applicable
Age: 21Years - 75Years
FEMALE
Healthy Volunteers
NCT03288207

Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments

Led by National Heart, Lung, and Blood Institute (NHLBI) · Updated on 2026-04-22

325

Participants Needed

1

Research Sites

423 weeks

Total Duration

On this page

Sponsors

N

National Heart, Lung, and Blood Institute (NHLBI)

Lead Sponsor

G

George Washington University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Background: Heart disease is a leading cause of death. People can reduce their heart disease risk by exercising more. Mobile health technology may make people more successful at increasing their exercise. This includes things like physical activity monitors and smartphone apps. Objective: To find out if mobile health technology can increase physical activity. Eligibility: African American women ages 21-75 who: * Are overweight or obese * Live in certain areas near Washington, DC * Have a smartphone that can use the study app Design: At visit 1, participants will * Answer survey questions. These may be about medical history, physical activity, and weight. They may also cover body image, health perception, and spirituality. * Have body size measured and get blood tests * Get a device to wear on the wrist. It will record physical activity and hours of sleep. * Learn how to download and use the study mobile app For 2 weeks, researchers will collect data about participants physical activity. Then participants will have a study visit with additional blood tests. All participants will get messages from the app that encourage exercise. Some participants will get data from the app about exercise near their home or work. Some participants may get face-to-face coaching. Participants may get wireless devices. These measure body weight, blood pressure, and blood glucose. Participants can measure these at home and upload the data to the app for the study. Participants will have visits after 3 and 6 months. They will repeat the visit 1 tests.

CONDITIONS

Official Title

Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments

Who Can Participate

Age: 21Years - 75Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • African American women aged 21 to 75 years
  • Overweight or obese with a body mass index (BMI) of 25 kg/m² or higher
  • Living in Washington, DC Wards 5, 7, or 8 or neighboring areas of Prince George's County, Maryland
  • Have access to a compatible smartphone to use the study mobile app
  • Able to provide informed consent independently
  • Able to speak and read English at an 8th grade level
Not Eligible

You will not qualify if you...

  • Medical conditions including heart failure, recent unintentional weight loss, or physical limitations that make physical activity unsafe
  • History of heart disease such as myocardial infarction in the past year, obstructive coronary artery disease, recent coronary artery stent placement, or severe structural heart disease with decompensation
  • Pregnant women or those not self-reporting negative pregnancy tests at screening, baseline, and follow-up visits unless postmenopausal or surgically sterile
  • Implanted metal objects or devices incompatible with MRI (for optional MRI testing)

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

National Institutes of Health Clinical Center

Bethesda, Maryland, United States, 20892

Actively Recruiting

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Research Team

M

Marie Marah, R.N.

CONTACT

T

Tiffany M Powell-Wiley, M.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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