Actively Recruiting

Age: 45Years - 79Years
All Genders
NCT06378619

Tapping Test and the Archimedean Spiral for the Differential Diagnosis of Tremor. Machine Learning Approach

Led by Consorci Sanitari de l'Alt Penedès i Garraf · Updated on 2025-06-26

110

Participants Needed

1

Research Sites

102 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In clinical practice, it is sometimes difficult to establish whether a patient's tremor is due to Parkinson's disease or essential tremor. The distinction is crucial as the health implications differ significantly between the two conditions. Therefore, the present study aims to develop a diagnostic method based on machine learning techniques to help differentiate whether a patient's tremor is due to one condition or the other. To achieve this, 110 patients with tremor, correctly diagnosed with either Parkinson's disease or essential tremor, will participate. They will undergo two diagnostic tests (tapping test and Archimedean spiral) to capture data that can be processed using machine learning techniques.

CONDITIONS

Official Title

Tapping Test and the Archimedean Spiral for the Differential Diagnosis of Tremor. Machine Learning Approach

Who Can Participate

Age: 45Years - 79Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ability to participate in necessary evaluations
  • Follow-up care at the Movement Disorders clinic of Hospital Sant Camil-Consorci Sanitari Alt Penedes i Garraf
  • Legal capacity to provide informed consent
  • Signed informed consent by participant or legal representative
  • Diagnosis meeting criteria for Group 1 or Group 2:
  • Group 1: Confirmed Parkinson's disease tremor diagnosis with bradykinesia and clinical stages 1-2 per Hoehn and Yahr
  • Group 2: Confirmed essential tremor diagnosis with positional plus kinetic/resting tremor, no bradykinesia, and at least 3 years of stable outpatient neurology follow-up
Not Eligible

You will not qualify if you...

  • Treatment with antipsychotics or antidepressants
  • Parkinson's disease patients with dyskinesias
  • Treatment with dopaminergic agonists or primidone
  • Tremor severity preventing continuous tracing
  • Cognitive or affective disorders limiting study participation
  • Participation in incompatible clinical studies
  • Diagnosed alcoholism affecting handwriting or causing neuropathy
  • Peripheral neuropathy of any cause
  • Dystonias
  • Previous stroke

AI-Screening

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Trial Site Locations

Total: 1 location

1

Hospital Sant Camil-Consorci Sanitari Alt'Pènedes i Garraf

Barcelona, Catalonia, Spain, 08810

Actively Recruiting

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Research Team

J

José Luis Camacho, MD

CONTACT

N

Noemí Casaponsa

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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