Actively Recruiting
Targeted Optical Biopsy for Local Rectal Scars in Rectal Cancer Patients After Neoadjuvant Chemoradiotherapy
Led by Nanfang Hospital, Southern Medical University · Updated on 2023-05-12
68
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Currently, low concordance (36%) is found between clinical complete response and pathologic complete response in patients with rectal cancer after neoadjuvant chemoradiotherapy. Probe-based confocal laser endoscopy (pCLE) provides a promising targeted optical biopsy to evaluate the response to neoadjuvant chemoradiotherapy. The aim of this study is to investigate whether pCLE-targeted optical biopsy can improve the accuracy of preoperative endoscopic biopsy for local rectal scars in rectal cancer patients after neoadjuvant chemoradiotherapy.
CONDITIONS
Official Title
Targeted Optical Biopsy for Local Rectal Scars in Rectal Cancer Patients After Neoadjuvant Chemoradiotherapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 and under 80 years
- American Society of Anesthesiology (ASA) score class I, II, or III
- Diagnosis of locally advanced rectal cancer
- Completion of standard neoadjuvant therapy
- Planned surgical resection
- Provided written informed consent
You will not qualify if you...
- Pregnant or breastfeeding women
- Acute renal insufficiency or stage II to IV chronic renal insufficiency
- Known allergic constitution
AI-Screening
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Trial Site Locations
Total: 1 location
1
Nanfang Hospital, Southern Medical University
Guangzhou, Guangdong, China, 510000
Actively Recruiting
Research Team
J
Jun Yan, M.D., Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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