Actively Recruiting
Targeting Apathy With Music in Parkinson's Disease
Led by University of British Columbia · Updated on 2026-03-23
50
Participants Needed
1
Research Sites
233 weeks
Total Duration
On this page
Sponsors
U
University of British Columbia
Lead Sponsor
N
Northeastern University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Parkinson's Disease (PD) is often accompanied by non-motor symptoms that make treatment more difficult. One such symptom is apathy (lack of motivation and emotion). There are no treatments for apathy in PD, and this remains a major unmet need in PD patients. One possible way to target apathy in PD patients is listening to music, which has been shown to help improve apathy in older adults. Little work has explored the mechanism in which music targets apathy. Thus, the goal of this study is to understand how music listening can impact the brain towards decreasing apathy in PD patients.
CONDITIONS
Official Title
Targeting Apathy With Music in Parkinson's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis of Parkinson's Disease following MDS Parkinson's disease criteria
You will not qualify if you...
- Diagnosis of atypical Parkinsonism such as Progressive supranuclear palsy or multiple system atrophy
- Epilepsy
- Other neurological diseases or complications such as myopathy, stroke, brain lesion, or multiple sclerosis
- Significant cognitive impairment (MoCa score less than 21)
- Moderate depression (Beck's Depression Inventory score greater than 20)
- Severe or multiple head traumas
- Presence of metal or medical implants including artificial heart valve, brain aneurysm clip, electrical stimulators, ear or eye implants, implanted drug infusion pump, coil, catheter, filter in blood vessels, orthopedic hardware, metallic prostheses, shrapnel, bullets, or metal fragments
- Recent surgery or tattoos including tattooed eyeliner in the last six weeks
- Cardiac pacemaker, wires, defibrillator, or ferromagnetic aneurysm clip
- History of injuries or brain surgery involving lodged metal in the eye or orbit
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Djavad Mowafghian Centre for Brain Health
Vancouver, British Columbia, Canada, V6T1Z3
Actively Recruiting
Research Team
M
Mikey Jose, B.Sc.
CONTACT
A
Annie Kuan
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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