Actively Recruiting

Phase Not Applicable
Age: 6Years - 12Years
All Genders
NCT04545606

Targeting Insomnia in School Aged Children With Autism Spectrum Disorder

Led by University of Missouri-Columbia · Updated on 2024-03-15

180

Participants Needed

1

Research Sites

515 weeks

Total Duration

On this page

Sponsors

U

University of Missouri-Columbia

Lead Sponsor

U

United States Department of Defense

Collaborating Sponsor

AI-Summary

What this Trial Is About

Children with Autism Spectrum Disorder (ASD) and insomnia, and their parent(s) will undergo 4 sessions of behavioral therapy for sleep problems followed by 4 bimonthly booster sessions. Children and their families will be randomly assigned to one of three conditions: cognitive behavioral therapy (in-person), cognitive behavioral therapy (remote), or behavioral therapy (remote). Arousal will be measured through heart-rate variability. Sleep and secondary outcomes (child daytime behavior, parent sleep) will be collected at baseline (weeks 1-2 before starting the treatment), post-treatment (weeks 6-8 from baseline), 6-month follow-up, and 12-month follow-up.

CONDITIONS

Official Title

Targeting Insomnia in School Aged Children With Autism Spectrum Disorder

Who Can Participate

Age: 6Years - 12Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Child is between 6 and 12 years old
  • Child has a verbal IQ of 70 or higher
  • Child's parent or legal guardian lives in the same home and participates in the study
  • Parent or guardian can read and understand English at a 5th-grade level
  • Child has a diagnosis of Autism Spectrum Disorder confirmed by standard diagnostic tools (ADOS and/or ADI-R)
  • Child has had insomnia symptoms (difficulty falling asleep, staying asleep, or early awakening) for 3 or more months
  • Child experiences daytime problems due to insomnia such as mood, cognitive, social, or academic difficulties
  • Sleep diaries and actigraphy show the child takes more than 30 minutes to fall asleep, wakes after sleep onset, or wakes early on at least 6 nights
Not Eligible

You will not qualify if you...

  • Parent cannot provide informed consent or child cannot provide assent
  • Unwillingness to accept random assignment to treatment groups
  • Participation in another randomized research study
  • Parent unable to complete forms or carry out treatment due to cognitive impairment
  • Untreated medical conditions including other sleep disorders like apnea, epilepsy, psychotic disorders, suicidal thoughts, or frequent parasomnias
  • Use of psychotropic or other sleep-altering medications except stimulants, sleep medications, or melatonin under specific conditions
  • Use of stimulants, sleep medications, or melatonin within the last month unless stabilized on them for 3 or more months
  • Participation in sleep treatments outside this trial
  • Parent reports child cannot tolerate Holter Monitoring or actigraphy due to sensitivity or behavioral issues
  • Other conditions that would negatively affect participation in the trial

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Thompson Center for Autism and Neurodevelopmental Disorders

Columbia, Missouri, United States, 65201

Actively Recruiting

Loading map...

Research Team

M

Melanie Stearns, PhD

CONTACT

S

Sydney Shoemaker, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here