Actively Recruiting
Targeting Osteosarcopaenia and Multimorbidity for Frailty Prevention
Led by Tan Tock Seng Hospital · Updated on 2025-04-11
500
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
Sponsors
T
Tan Tock Seng Hospital
Lead Sponsor
R
Rehabilitation Research Institute of Singapore (RRIS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aging population and its accompanying burden from non-communicable chronic diseases predicts an increasing impact imposed by frailty on healthcare systems. This is due to a lack of normative data for older adults and reliable risk stratification methods to develop effective approaches to the prevention of frailty. In this study, the investigators plan to form a common dataset for phenotype identification, risk stratification of frailty and its targeted treatment plans in the at-risk and mildly frail population.
CONDITIONS
Official Title
Targeting Osteosarcopaenia and Multimorbidity for Frailty Prevention
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 50 years or older
- Asian ethnicity
- First diagnosis of stroke, traumatic brain injury, knee osteoarthritis, or breast cancer
- Living in the community
- Able to understand simple one-step commands
- For inpatients: within 12 weeks of stroke or traumatic brain injury onset and within 2 weeks of rehabilitation ward admission
- For outpatients: more than 6 months from initial diagnosis of stroke, traumatic brain injury, knee osteoarthritis, or breast cancer and able to ambulate with at least standby assistance or independently
You will not qualify if you...
- Living in a nursing home or dormitory
- Non-resident status in Singapore (e.g., foreign worker, tourist, temporary visit pass)
- Severe deafness, severe visual impairment, or severe/global aphasia affecting understanding of questionnaires and tasks
- Active fractures, dislocations, non-weight-bearing status, burns, unhealed wounds, active skin infections or eczema, agitated behavior, or delirium
- Life expectancy less than 1 year
- Presence of tracheostomy, ventilator dependence, renal dialysis, or end-organ failure
- Disorders of consciousness
- Pregnant or lactating participants
- For knee osteoarthritis patients only: alternative diagnosis to knee OA such as referred pain from hip or spine
- Other types of knee arthritis such as inflammatory or post-traumatic
- Previous knee arthroplasty
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Tan Tock Seng Hospital
Singapore, Singapore, Singapore, 308433
Actively Recruiting
Research Team
L
Low Ai Mei Jaclyn
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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