Actively Recruiting

Phase Not Applicable
Age: 14Years - 20Years
All Genders
NCT05131035

Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk

Led by Northwell Health · Updated on 2025-11-24

54

Participants Needed

1

Research Sites

239 weeks

Total Duration

On this page

Sponsors

N

Northwell Health

Lead Sponsor

N

National Institute of Mental Health (NIMH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This 10 week intervention, Specific Cognitive Remediation with Surround (or SCORES), is designed to target processing speed, a cognitive domain related directly to social functioning, which in turn, represents a vulnerability factor for psychosis. This remotely-delivered intervention combining targeted cognitive training exercises and group support was developed to directly impact processing speed, and at the same time, boost motivation and engagement in adolescents at risk for schizophrenia and other psychotic disorders.

CONDITIONS

Official Title

Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk

Who Can Participate

Age: 14Years - 20Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Meet Clinical High Risk (CHR) criteria on the Structured Interview for Psychosis Risk Syndromes, defined by the presence of at least one attenuated positive symptom at a moderate to severe level
  • A score representing 0.5 standard deviations below the mean on Animal Naming, Trails A, or BACS: Symbol Coding from the MATRICS Consensus Cognitive Battery (MCCB)
Not Eligible

You will not qualify if you...

  • Any DSM 5 Schizophrenia-Spectrum diagnosis
  • Non-English speaking
  • Past or current history of a clinically significant central nervous system disorder (e.g., seizure disorder)
  • Estimated IQ less than 70
  • Significant head injury
  • Significant substance abuse
  • Significant visual or auditory impairment

AI-Screening

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Trial Site Locations

Total: 1 location

1

Northwell Health- The Zucker Hillside Hospital

Glen Oaks, New York, United States, 11042

Actively Recruiting

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Research Team

R

Ricardo E Carrion, Ph.D.

CONTACT

D

Danielle McLaughlin, M.A.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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