Actively Recruiting

Phase Not Applicable
Age: 8Years - 13Years
All Genders
NCT06645587

Targeting Repetitive Behaviors in Autism Spectrum Disorder Via Transcranial Direct Current Stimulation

Led by Bambino Gesù Hospital and Research Institute · Updated on 2024-10-17

78

Participants Needed

1

Research Sites

77 weeks

Total Duration

On this page

Sponsors

B

Bambino Gesù Hospital and Research Institute

Lead Sponsor

M

Ministero della Salute, Italy

Collaborating Sponsor

AI-Summary

What this Trial Is About

Repetitive behaviors (RBs) are a prevalent feature of Autism Spectrum Disorder (ASD). There are two groups of RBs: lower-order (e.g. motor stereotypies) and higher-order RBs (e.g. restricted interests), linked to sensory-motor and the associative loops, respectively. To date, treatment options for RBs are very limited. High-definition transcranial direct current stimulation (HD-tDCS) may be effective in reducing the impact of RBs in children with ASD by targeting the associated brain alterations. Moreover, the high focality of HD-tDCS will help the investigators to disentangle the relative contribution of different brain loops (namely, sensory-motor and the associative loops) into RBs subtypes. The investigators will also study the electrophysiological patterns associated to behavioral changes after the application of HD-tDCS.

CONDITIONS

Official Title

Targeting Repetitive Behaviors in Autism Spectrum Disorder Via Transcranial Direct Current Stimulation

Who Can Participate

Age: 8Years - 13Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants diagnosed with Autism Spectrum Disorder (ASD) based on DSM-5 and clinical evaluation
  • Both genders are eligible
  • Intelligence quotient (IQ) of 70 or higher
  • Age between 8 years and 13 years 11 months inclusive
Not Eligible

You will not qualify if you...

  • Presence of neurological, medical, or genetic conditions such as brain tumors or genetic syndromes
  • Personal or family history of epilepsy
  • Other primary psychiatric diagnoses like bipolar disorder, schizophrenia spectrum disorders, or adjustment disorder
  • Sensorimotor deficits
  • Presence of pacemaker or metal devices in the body
  • Currently taking central nervous system (CNS)-active medications
  • Receiving cognitive-behavioral therapies focused on repetitive behaviors within 3 months prior to the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Bambino Gesù Children Hospital

Rome, Italy, Italy, 00152

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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