Development and validation of a chemotherapy-induced taste alteration scale.
Taro Kano, Kiyoko Kanda
https://pubmed.ncbi.nlm.nih.gov/23448748Actively Recruiting
Led by Wake Forest University Health Sciences · Updated on 2026-05-22
400
Participants Needed
1
Research Sites
N/A
Total Duration
This research aims to improve understanding and management of taste changes caused by chemotherapy in adult cancer patients. It evaluates whether adding a nurse-led, detailed taste alteration assessment and education helps patients detect and manage these taste changes better than usual care. The study includes a diverse group of cancer patients undergoing chemotherapy, focusing on taste alteration symptoms, patient actions, and dietary intake. Participants receive care based on their clinic's assignment: usual care or an intervention with nurse-led self-assessment and self-management of taste alterations. The intervention uses a validated taste assessment tool (Chemotherapy-induced Taste Alterations Scale) and patient education materials to help manage symptoms. Usual care includes standard chemotherapy education and a simple taste alteration severity question. Data collection occurs before chemotherapy starts, through the first four chemotherapy cycles, and continues for six months. Participants complete baseline assessments and patient education, report taste alteration symptoms during chemotherapy visits, and work with nurse coaches. The study tracks taste alteration severity, patient interventions, dietary intake, and body mass index over six months. Data collection and patient support continue throughout the chemotherapy cycles and follow-up period to assess the intervention's impact on symptom management and nutrition.
CONDITIONS
Taste Alterations Study
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - During the first 4 chemotherapy cycles over approximately 6 months
Participants receive chemotherapy and either usual care or a nurse-led intervention involving taste alteration self-assessment and self-management strategies to help manage taste alterations during chemotherapy.
Visits aligned with chemotherapy cycles, approximately 4 cycles over 6 months
Duration - Up to 6 months following treatment initiation
Participants are monitored for taste alteration severity, dietary intake, and body mass index through the completion of the study.
Ongoing assessments during treatment visits up to 6 months
Total: 1 location
1
Advocate Illinois Masonic Medical Center
Chicago, Illinois, United States, 60657
Actively Recruiting
M
Mary L Hook, PhD, RN
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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