Actively Recruiting
The Taste-Mood Diagnostic Study
Led by Ranvier Health Ltd · Updated on 2024-06-12
240
Participants Needed
4
Research Sites
142 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study looks at whether a taste test device can be used as a diagnostic aid for depression. Taste tests will be carried out before and after first use of an antidepressant (prescribed by the patient's GP) and then again six to eight weeks later a further taste test will be conducted. The results of these tests will be assessed to see if they correlate with the outcome of validated mood questionnaires carried out at the first and second visits.
CONDITIONS
Official Title
The Taste-Mood Diagnostic Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients diagnosed with untreated Major Depressive Disorder (MDD) for at least 3 weeks or new/recurrent MDD untreated in this episode
- Patients needing medication treatment for MDD
- No significant other mental or physical illnesses such as psychosis or receiving end of life care
- Stable medical therapy for at least 30 days before screening
- Willing and able to attend all visits and follow study procedures
- Not infected with coronavirus or requiring self-isolation
- Able to understand study requirements and provide written informed consent
You will not qualify if you...
- Currently taking antidepressant medication
- Known or suspected allergy or intolerance to probe drugs or their ingredients
- History or presence of cardiac, eye, gastrointestinal, liver, kidney diseases, or other conditions increasing risk from probe drugs
- History or presence of neurological or psychiatric disorders such as stroke, brain injury, epilepsy, multiple sclerosis, Parkinson's disease, vascular dementia, transient ischemic attack, or schizophrenia
- Diagnosis of chronic pain
- Participation in another clinical trial within 30 days that interferes with this study
- Pregnant, likely to become pregnant, or breastfeeding
- Using supplements with psychoactive herbs like St John's Wort or 5-HTP
- Regular use of psychoactive stimulants or recreational drugs like MDMA, amphetamine, LSD, or cocaine
- Infected with coronavirus or advised to self-isolate
- Unable or unwilling to comply with study procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Jhoots Pharmacy
Bristol, Avon, United Kingdom, BS9 3AG
Actively Recruiting
2
Honiton Surgery
Honiton, Devon, United Kingdom, EX14 2LY
Actively Recruiting
3
Humber Teaching NHS Foundation Trust
Hull, Yorkshire, United Kingdom
Actively Recruiting
4
West Walk Surgery, Yate
Bristol, United Kingdom, BS37 4AX
Actively Recruiting
Research Team
H
Helen Leach, BDS, MSc
CONTACT
D
David Adams, MBBS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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