Actively Recruiting

Phase Not Applicable
Age: 18Years - 55Years
All Genders
NCT02902198

Taste Physiology in Obese Volunteers Before and After Bariatric Surgery

Led by University Hospital, Basel, Switzerland · Updated on 2025-04-03

16

Participants Needed

1

Research Sites

678 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objective is to investigate neuro-anatomical correlates of gastrointestinal taste stimulation by means of functional MRI before and after bariatric surgery. Intragastric administration of glucose, monosodium glutamate, chloroquine and placebo is followed by functional brain MRI in obese humans before and 3 months after surgery.

CONDITIONS

Official Title

Taste Physiology in Obese Volunteers Before and After Bariatric Surgery

Who Can Participate

Age: 18Years - 55Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Morbidly obese patients with a body mass index (BMI) of at least 35 kg/m2 scheduled for bariatric surgery
  • Right-handed individuals
  • Age between 18 and 55 years
Not Eligible

You will not qualify if you...

  • Presence of cardiovascular disease
  • History of neurologic or psychiatric disorders

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hopital Basel

Basel, Switzerland

Actively Recruiting

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Research Team

B

Bettina Wölnerhanssen, Dr

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

8

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Taste Physiology in Obese Volunteers Before and After Bariatric Surgery | DecenTrialz