Actively Recruiting
Taurine Effect on Glycemic, Lipidic and Inflammatory Profile in Individuals With Type 2 Diabetes
Led by Hospital de Clinicas de Porto Alegre · Updated on 2025-09-19
94
Participants Needed
1
Research Sites
233 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Type 2 diabetes mellitus (DM2) is characterized by chronic hyperglycemia, which is a risk factor for comorbidities and death. Although conventional pharmacotherapy is effective, some individuals do not reach the glycemic targets, requiring adjuvant therapies. Taurine is a semi-essential amino acid with antioxidant and osmoregulatory properties, commonly used as a nutritional supplement. Pre-clinical studies show its effectiveness in reducing blood glucose and cholesterol, but there are no well-conducted clinical studies evaluating the effect of taurine on glycated hemoglobin. Additionally, animal models showed that taurine had a protective effect from diabetic nephropathy. The hypothesize of this study is that taurine administration improves the glycemic, lipid, inflammatory, and anthropometric parameters in DM2 individuals.
CONDITIONS
Official Title
Taurine Effect on Glycemic, Lipidic and Inflammatory Profile in Individuals With Type 2 Diabetes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female and male individuals, with clinical diagnosis of DM2 for at least 6 months
- Age over 30 years
- BMC equal to or above 18.5 kg/m2, without weight change in the last 3 months
- HbA1c between 7.5% and 10.5%
You will not qualify if you...
- Use of herbal supplements, antioxidants, and multivitamins in the last 3 months
- Pregnancy or lactation
- Chronic renal failure with glomerular filtration rate calculated by MDRD < 30 mL/h
- Myocardial infarction in the last than 6 months
- Current neoplasia
- Chronic use of glucocorticoids
- Bariatric surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hospital de Clínicas
Porto Alegre, Rio Grande do Sul, Brazil, 90630090
Actively Recruiting
Research Team
B
Beatriz D Schaan, PhD
CONTACT
R
Rosane Gomez, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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