Actively Recruiting
TAVR: The Impact of Prothesis Positioning on Valvular and Coronary Hemodynamics
Led by Heinrich-Heine University, Duesseldorf · Updated on 2025-03-26
100
Participants Needed
1
Research Sites
62 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this clinical study is to learn more about the effects of TAVR-prosthesis positioning on hemodynamics and the coronary arteries. The main questions it aims to answer are: 1. Does the cardiac magnetic resonance imaging and the echocardiography imaging provide an equivalent alternative to the computer tomography which is the state of the art in evaluating commissural alignment? 2. What effect does the position of the valve on the annular level have, especially its symmetrical and commissural position, on valvular and aortic blood flow characteristics? 3. What is the influence of symmetrical position and the presence of a commissural alignment on the coronary flow after transcatheter aortic valve replacement?
CONDITIONS
Official Title
TAVR: The Impact of Prothesis Positioning on Valvular and Coronary Hemodynamics
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients who have undergone transfemoral transcatheter aortic valve replacement (TAVR).
You will not qualify if you...
- Use of any access route other than transfemoral for TAVR.
- Valve-in-valve procedures.
- History of prior bioprosthetic valve implantation.
- Presence of pacemaker, implantable cardioverter-defibrillator (ICD), or cardiac resynchronization therapy (CRT) system.
- Diagnosis of liver cirrhosis.
- Esophageal disorders, including but not limited to esophageal varices.
- Thrombocytopenia or coagulation disorders.
- Any medical or psychiatric condition that may impair ability to give informed consent or interfere with study procedures, including dementia, alcoholism, or substance abuse.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Division of Cardiology, Pulmonary Disease and Vascular Medicine at University Hospital Duesseldorf
Düsseldorf, Germany, 40225
Actively Recruiting
Research Team
T
Tobias Zeus, Prof
CONTACT
K
Kathrin Klein, Dr. med.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here