Actively Recruiting

Phase Not Applicable
Age: 50Years - 89Years
All Genders
NCT06562127

TBI Rehabilitation and Activation in Veterans

Led by Northern California Institute of Research and Education · Updated on 2025-05-16

120

Participants Needed

2

Research Sites

142 weeks

Total Duration

On this page

Sponsors

N

Northern California Institute of Research and Education

Lead Sponsor

S

San Francisco Veterans Affairs Medical Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

This trial will evaluate the impact of a multicomponent program (TBI Rehabilitation and Activation in Veterans; TRAIN-Vets) on improving cognitive function over an 8-month trial period in older Veterans with traumatic brain injury (TBI). Older Veterans with a history of TBI and subjective cognitive complaints will be enrolled and randomly assign to either the TRAIN-Vets intervention (consisting of aquatic-based exercise training, cognitive training, and lifestyle coaching) or the Health Education Control, where they will receive educational materials about brain health and healthy lifestyles.

CONDITIONS

Official Title

TBI Rehabilitation and Activation in Veterans

Who Can Participate

Age: 50Years - 89Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Veteran aged between 50 and 89 years
  • History of mild or moderate traumatic brain injury more than 6 months ago
  • Sufficient vision and hearing to complete cognitive testing
  • Willingness to participate in an 8-month water-based exercise and cognitive training program
  • Approval from primary medical provider to take part in water-based exercise
  • Self-reported subjective cognitive complaints
  • English proficiency sufficient for cognitive testing
  • Access to an internet-connected device for testing and cognitive training
Not Eligible

You will not qualify if you...

  • Current severe and unstable psychiatric disorder
  • Diagnosis of dementia, Montreal Cognitive Assessment score below 18, or delirium
  • Traumatic brain injury within the past 6 months
  • Acute illness or unstable chronic illness
  • Current severe cardiac disease
  • Severe traumatic brain injury or open head injury
  • Inability to exercise consistently
  • Inability to read, understand, and voluntarily sign informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

VA Palo Alto Health Care System

Palo Alto, California, United States, 94304-1207

Actively Recruiting

2

San Francisco VA Health Care System

San Francisco, California, United States, 94121

Actively Recruiting

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Research Team

C

Carrie Peltz, PhD

CONTACT

J

Julia Cheunkarndee

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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