Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
NCT07112521

tDCS Intervention in Breast Cancer Survivors With and Without Obesity Reporting Cognitive Impairment

Led by University of Helsinki · Updated on 2025-09-02

40

Participants Needed

1

Research Sites

69 weeks

Total Duration

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AI-Summary

What this Trial Is About

The goal of this intervention is to investigate whether transcranial Direct Current Stimulation (tDCS) can alleviate Cancer-Related Cognitive Impairment (CRCI) in breast cancer survivors, as measured by changes in brain structures and cognitive performance. To assess the efficacy of tDCS, the investigators will compare outcomes between participants receiving active stimulation and those receiving sham stimulation (a placebo condition where participants believe they are receiving stimulation, but are not). Participants will: * Undergo a baseline MRI session * Receive either active or sham tDCS for six weeks * Undergo a follow-up MRI session * Complete cognitive tests and respond to psychosocial questionnaires before, during, and after the tDCS intervention

CONDITIONS

Official Title

tDCS Intervention in Breast Cancer Survivors With and Without Obesity Reporting Cognitive Impairment

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female
  • Age 18 years or older
  • Diagnosed with primary adult-onset breast cancer within the last 5 years
  • Completed all active cancer treatments at least 3 months before the study
  • Able to fulfill study requirements, including internet access
  • Fluent in Finnish or English
  • Have normal or corrected vision and hearing
  • Right-handed as determined by Edinburgh Handedness Inventory score
Not Eligible

You will not qualify if you...

  • Received primary cancer treatment within the last 3 months
  • History of childhood-onset cancer
  • Have acute eczema on the scalp
  • Diagnosed with dementia, Alzheimer's disease, multiple sclerosis, or Parkinson's disease
  • Experienced unconsciousness for more than 5 minutes due to head/brain injury in the last 10 years
  • History of stroke or transient ischemic attack
  • Suffer from claustrophobia
  • Pregnant or breastfeeding
  • Have medical implants or devices such as cardiac devices, metallic intraocular bodies, neurostimulation systems, cochlear implants, drug pumps, catheters with metal, metallic fragments, cerebral aneurysm clips, magnetic dental implants, tissue expanders, artificial limbs, non-removable piercings, or face tattoos
  • Weigh over 250 kg or cannot fit inside the MRI machine bore

AI-Screening

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Trial Site Locations

Total: 1 location

1

Department of Psychology, Faculty of Medicine, University of Helsinki

Helsinki, Uusimaa, Finland, 00200

Actively Recruiting

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Research Team

M

Manon Chédeville, Doctoral Researcher

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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