Actively Recruiting

Phase Not Applicable
Age: 12Years - 25Years
All Genders
Healthy Volunteers
NCT06294184

TDCS Interventions for Subthreshold Depressive Symptoms in Young Individuals.

Led by Guangzhou Psychiatric Hospital · Updated on 2024-12-12

150

Participants Needed

1

Research Sites

108 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to assess the mechanisms of the effect of transcranial direct current stimulation (tDCS) in alleviating subthreshold depressive symptoms in young individuals, and individualized outcome prediction is carried out.

CONDITIONS

Official Title

TDCS Interventions for Subthreshold Depressive Symptoms in Young Individuals.

Who Can Participate

Age: 12Years - 25Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Be between the ages of 12-25
  • Be right-handed according to the Edinburgh Handedness Inventory
  • Have 2-4 depressive symptoms lasting more than 1 week, or more than 5 symptoms lasting more than 1 week but less than 2 weeks, not meeting major depressive episode criteria
  • Have a Hamilton Depression Scale (HAMD-24) score of 8 to less than 24 points
  • Any gender
  • Voluntarily participate and provide signed informed consent
Not Eligible

You will not qualify if you...

  • Diagnosed with psychiatric disorders due to organic causes, substance-related disorders, neurodevelopmental disorders, schizophrenia spectrum or other psychotic disorders, or bipolar disorder
  • Have two or more manic symptoms for 4 days without hypomania, or hypomanic symptoms for only 2-3 days
  • Severe or unstable physical illness
  • Moderate or higher suicide risk
  • Received tDCS in the past 3 months with continuous intervention over 2 weeks
  • Contraindications to tDCS such as brain implants or a personal/family history of epilepsy
  • Contraindications to MRI such as in vivo metal implants

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Guangzhou Brain hospital(Guangzhou Huiai Hospital)

Guangzhou, Guangdong, China, 510370

Actively Recruiting

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Research Team

K

Kangguang Lin, M.D;Ph.D

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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TDCS Interventions for Subthreshold Depressive Symptoms in Young Individuals. | DecenTrialz