Teaching Health Promotion and Resilience in Varied Environments: a Peer-led Intervention Following Hospital Discharge

What this Trial Is About

Researchers are evaluating a peer-led health resilience and promotion program called the THRIVE intervention for people with opioid use disorder. The study aims to find out if participants receiving the THRIVE intervention have fewer self-reported non-fatal overdoses or skin and soft tissue infections compared to those receiving enhanced usual care. The study is sponsored by the University of Pennsylvania and focuses on support following hospital discharge. Participants in the THRIVE intervention group will receive one in-person session from a peer support specialist while in the hospital, followed by weekly text messages for 12 weeks. They will also answer monthly multiple-choice assessments via text at months 1 through 6. Participants in the enhanced usual care group will receive a handout with health resilience education and local resources and will complete the same monthly text assessments. Both groups will complete baseline, 3-month, and 6-month assessments with research assistants. Throughout the study, participants will be monitored through self-reported surveys and assessments to track the incidence of non-fatal overdoses and skin or soft tissue infections. The primary outcome compares these outcomes from baseline to 6 months between the two groups. Participants will be evaluated at multiple time points, with data collected via text messages and in-person assessments, allowing researchers to measure the effectiveness of the THRIVE intervention over half a year.

Teaching Health Resilience in a Hospital Setting: A Peer-led Intervention