Actively Recruiting
TEAS Combined With Triple Antiemetic Drugs to Prevent PONV in High-Risk Patients
Led by Zhejiang University · Updated on 2026-03-18
780
Participants Needed
1
Research Sites
93 weeks
Total Duration
On this page
Sponsors
Z
Zhejiang University
Lead Sponsor
J
Jinhua Central Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to evaluate the effects of transcutaneous electrical acupoint stimulation (TEAS) combined with triple antiemetics for postoperative nausea and vomiting (PONV) in high-risk patients. The primary question it seeks to answer is: Does TEAS combined with triple antiemetics further reduce the incidence of PONV in high-risk subjects? Researchers will compare active TEAS with sham stimulation to determine whether the addition of TEAS to dexamethasone, palonosetron, and droperidol lowers the PONV rate beyond that achieved by the triple-drug prophylaxis alone.
CONDITIONS
Official Title
TEAS Combined With Triple Antiemetic Drugs to Prevent PONV in High-Risk Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women scheduled for laparoscopic surgery
- Aged 18-65 years
- ASA Class I-III
- Apfel score 23 3 (female sex, non-smoker, history of PONV and/or motion sickness)
You will not qualify if you...
- History of allergy to the investigational drug or contraindications
- Long-QT syndrome
- Pregnancy, lactation, or menstruation
- Current smoker
- Nausea/vomiting or use of antiemetics, opioids, or systemic corticosteroids within 24 hours before surgery
- Requirement for post-operative sedation and mechanical ventilation
- Severe renal or hepatic impairment
- Psychiatric or neurological disorder
- Vertebrobasilar insufficiency
- Vestibular disease
- Language or communication barrier
- Skin lesion or infection at the acupoint stimulation site
- Upper-limb nerve injury
- Implanted cardiac pacemaker or defibrillator
- Participation in another clinical trial within the past 4 weeks
AI-Screening
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Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310000
Actively Recruiting
Research Team
D
Diansan Su, PhD
CONTACT
D
Dongdong Tian
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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