Testing a New Low Energy Cardiovascular MRI Scanner System Comparing Image Quality in Adults With and Without Heart or Other Diseases

What this Trial Is About

Researchers are evaluating a new type of magnetic resonance imaging MRI scanner that uses lower energy levels than conventional MRI machines. This low specific absorption rate SAR scanner aims to produce high-quality images of the heart and other organs while reducing heating of metal implants. The study includes healthy adults and adults with known heart or non-heart diseases to test the safety and accuracy of this new MRI technology. Participants will undergo MRI scans using the new low SAR system, and some will also have scans with a conventional MRI for comparison. Scans may include the use of gadolinium dye to enhance image quality and a vasodilator drug to assess blood flow in the heart. The scanning process involves lying inside the MRI machine for up to two hours, holding breath for short periods, and using sensors to monitor heart and breathing activity. During the study, participants will have blood tests and multiple MRI sessions within 60 days if both scanner types are used. The research team will measure the technical feasibility and image quality of the new MRI compared to standard MRI. The study will also monitor participants for safety and collect various health information over a period of up to 72 months to assess the long-term performance of the low SAR MRI system.

Technical Development of Cardiovascular Magnetic Resonance Imaging (CMR) Using a Low Specific Absorption Rate (SAR) Scanner System