Actively Recruiting

Phase Not Applicable
Age: 0 - 79Years
MALE
NCT06754488

A Technique Improves Urinary Continence in Patients Undergoing Laparoscopic Radical Prostatectomy

Led by Suzhou Municipal Hospital · Updated on 2024-12-31

120

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Laparoscopic radical prostatectomy (LRP) is the main treatment method for early prostate cancer, and postoperative urinary incontinence is one of the main complications after LRP. Urologists have applied various new operations in clinical practice to improve the urinary incontinence of patients after LRP surgery, but urinary incontinence is still the main problem affecting the quality of life of patients after surgery. In recent years, we have found that the new bladder neck urethral reconstruction method adopted by our department in LRP surgery can effectively improve the postoperative urinary incontinence of patients. In this study, a randomized controlled trial was intended to verify that the new bladder and neck urethral reconstruction technique could effectively improve early urinary control in patients after radical laparoscopic prostatectomy, and the patients were randomly divided into four groups by factorial design: posterior reconstruction group, posterior reconstruction +anterior suspension group, Sham group, and anterior suspension group to further verify the influencing factors of improved urinary control. The aim is to prove that the new operation can effectively reduce the urinary incontinence rate of patients after LRP, and analyze the mechanism of the new operation to improve the urinary incontinence of patients after LRP, and provide a new idea for the reconstruction of bladder neck and urethra during laparoscopic radical prostatectomy.

CONDITIONS

Official Title

A Technique Improves Urinary Continence in Patients Undergoing Laparoscopic Radical Prostatectomy

Who Can Participate

Age: 0 - 79Years
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Preoperative needle biopsy confirmed prostate cancer
  • Clinical stage T1 or T2
Not Eligible

You will not qualify if you...

  • Diseases that significantly increase the risk of surgery or anesthesia, such as severe cardiovascular diseases, respiratory diseases, and coagulation disorders
  • Extensive bone metastasis or metastases to other organs
  • History of urinary incontinence or transurethral resection of the prostate
  • Tumor invasion of the bladder neck

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Suzhou Municipal Hospital

Suzhou, Jiangsu, China, 215000

Actively Recruiting

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Research Team

T

Tengyue Zeng, doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

TREATMENT

Number of Arms

4

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