Actively Recruiting
Technology-Assisted Early Mobilization Program Among Patients in the Intensive Care Units
Led by Hsiao-Yean Chiu · Updated on 2026-03-09
138
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
Sponsors
H
Hsiao-Yean Chiu
Lead Sponsor
T
Taipei Medical University Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
This single-blind, three-group parallel randomized controlled trial will involve 138 patients with critical illness, randomly assigned at a 1:1:1 ratio to the technology-assisted early mobilization group (46 patients), the systematic early mobilization group (46 patients), or the control group (46 patients). The technology-assisted early mobilization group will receive interventions within 72 hours of ventilator use. The interventions include protocol-oriented early mobilization program carried out by physiotherapist and researcher and technology-assisted in-bed activities primarily assisted by family members. The systematic early mobilization group will receive only the similar protocol-oriented early mobilization program within 72 hours of ventilator use. The control group will receive routine rehabilitation as usual. The primary outcomes include occurrence of intensive care unit-acquired weakness (ICUAW). Secondary outcomes include muscle strength, delirium, sleep status, clinical outcomes, activities of daily living, and quality of life. Measurements will be assessed on the day of enrollment, during the ICU stay, on the day of ICU discharge (or up to 28 days), on the day of hospital discharge, and six months after hospital discharge.
CONDITIONS
Official Title
Technology-Assisted Early Mobilization Program Among Patients in the Intensive Care Units
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 years or older
- Receiving mechanical ventilation for at least 24 hours
- Richmond Agitation-Sedation Scale (RASS) score between 0 and -1
- No vision, hearing, or body movement restrictions
- Clear consciousness and ability to communicate in Chinese
- Expected to remain in the ICU for more than 96 hours
You will not qualify if you...
- Developed delirium before enrollment (ICDSC score greater than 4)
- Acute physiology and chronic health evaluation (APACHE II) score greater than 25 within 24 hours after ICU admission
- Muscle weakness caused by severe acute brain injury such as traumatic brain injury or stroke, spinal cord injury, other neuromuscular diseases, long-term bedridden status, or hemiplegia
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Taipei Medical University Hospital
Taipei, Taiwan, 110
Actively Recruiting
Research Team
H
Hsiao-Yean Chiu, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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