Remote Exercise Program to Improve Brain Function and Fitness in Adults 60 and Older With Small Vessel Disease and Lacunar Stroke

What this Trial Is About

Researchers are evaluating the effects of a remotely delivered exercise program on brain functional connectivity and physical fitness in patients with small vessel disease SVD-related ischemic stroke. This prospective, randomized, multicenter trial will include patients aged 60 and older who have a history of lacunar stroke, minimal disability, and low physical activity levels. The study aims to understand how exercise may influence brain function and physical health in this population. Participants will be randomly assigned to one of two groups a 24-week telecoached exercise intervention or usual care. The exercise program consists of multicomponent physical exercises delivered remotely twice a week. After the initial 24 weeks, the control group will also receive the exercise intervention, allowing the assessment of immediate and lasting effects. Assessments occur at baseline, 12 weeks, 24 weeks, and 48 weeks. During the study, participants will undergo evaluations including brain connectivity measured by high-density EEG and physical fitness tests such as the Senior Fitness Test. Researchers will also monitor physical activity levels, body measurements, blood pressure, and heart rate. The trial includes adherence support through telecoaching and aims to gather comprehensive data on both neurophysiological and clinical outcomes over the study period.

Telecoached Exercise Intervention for Connectivity Enhancement in Small Vessel Disease (TELECONNECT-SVD)