Actively Recruiting
Telehealth Exercise Program Evaluating Fatigue and Physical Function in Rural Cancer Survivors
Led by University of Colorado, Denver · Updated on 2026-02-05
134
Participants Needed
2
Research Sites
268 weeks
Total Duration
On this page
Sponsors
U
University of Colorado, Denver
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study investigates the efficacy of a telehealth exercise program designed specifically for rural cancer survivors with cancer-related fatigue (CRF). Small dried blood samples and measures of physical function will be collected throughout the program. The main questions it aims to answer are: * Does the exercise program improve CRF in rural cancer survivors? * How do CRF, metabolism, and physical function change during the exercise program? Researchers will compare the program to a wait-list control group. This group will complete all study measures without without changing current physical activity before receiving the full exercise program. Participants will: * Complete a virtual physical assessment before and after the program. * Complete brief virtual assessments and collect dried blood samples (at home and mailed in) every two weeks during the program. * Receive a personalized exercise program including virtual sessions and remote exercise programming with a cancer exercise specialist (after a 12-week wait period in the wait-list control group). * Optional: Willing participants will visit a study site for a laboratory-based exercise assessment before and after the program.
CONDITIONS
Official Title
Telehealth Exercise Program Evaluating Fatigue and Physical Function in Rural Cancer Survivors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older and under 90 years of age.
- Diagnosis of breast or prostate cancer.
- Completed cancer treatment with curative intent more than 3 months and less than 5 years before study start.
- Cancer treatment includes hormonal, radiation, chemotherapy, and/or immunotherapy; surgery only is not eligible.
- Breast cancer patients currently on maintenance hormonal therapy with no planned treatment changes in the next 6 months are eligible.
- Home zip code meets HRSA definition of rural.
- Have at least moderate fatigue (greater than 3 out of 10).
- Access to high-speed home internet.
- Own a smartphone or laptop with a front-facing camera.
- Able and willing to give informed consent.
- Willing to participate in a 12-week telehealth exercise program or 12-week wait period with remote assessments every 2 weeks.
- Able and willing to provide contact information for a local support person.
- Able and willing to provide contact information for a local primary care provider.
- Able to provide signed physician clearance for exercise if indicated by screening questionnaires.
You will not qualify if you...
- Eastern Cooperative Oncology Group (ECOG) Performance Status Grade 2 or higher.
- Current or planned cancer-related treatments in the next 6 months, except maintenance hormonal therapies.
- Prostate cancer patients currently receiving androgen deprivation therapy (ADT) or with prior ADT treatment lasting 12 months or more are not eligible.
- Plans to move to a non-rural area within the next 6 months.
- Presence of any disease or condition that makes exercise unsafe, such as recent cardiac event or chronic obstructive pulmonary disease.
- Presence or history of metabolic disease like diabetes or uncontrolled thyroid disorders.
- Participation in another exercise oncology program at this time.
AI-Screening
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Trial Site Locations
Total: 2 locations
1
University of Colorado Anschutz Medical Campus
Aurora, Colorado, United States, 80045
Actively Recruiting
2
University of Montana
Missoula, Montana, United States, 59812
Actively Recruiting
Research Team
J
Jared Scorsone
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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